| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 39 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:13:00 | USP39 Serves as a Deubiquitinase to Stabilize and Sustains Type I IFN-Induced Antiviral Immunity. | 33127822 |
| 2021-03-06 13:30:00 | Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung through Activating the p53 Pathway. | 33255748 |
| 2020-04-18 11:47:00 | USP39 promotes the development of human leukemia by regulating cell cycle, survival, and proliferation of the cells. | 30898977 |
| 2020-02-01 11:27:00 | USP39 has oncogenic properties that increase TAZ protein levels by inducing maturation of its mRNA. USP39 therefore provides a novel therapeutic target for the treatment of human glioma. | 31332287 |
| 2020-01-25 14:47:00 | Results demonstrated that USP39 deubiquitinates and stabilizes CHK2, which in turn regulates cell cycle checkpoint, cell apoptosis and chemo-radiation response. Furthermore, USP39 and CHK2 are correlatively downregulated in lung cancer, suggesting a potential prognostic role of USP39 in lung cancer. | 30771428 |
| Type | IDs |
|---|---|
| Synonymous | 65K, CGI-21, HSPC332, SAD1, SNRNP65 |
| Gene |
UniProtKB-ID:
SNUT2_HUMAN,
B7Z7L9_HUMAN,
A0A087X1B2_HUMAN,
B3KMG1_HUMAN,
B3KPG7_HUMAN
UniprotKB:
Q53GS9,
B7Z7L9,
A0A087X1B2,
B3KMG1,
B3KPG7
UniParc:
UPI000191511A,
UPI0000073448,
UPI000003771A,
UPI000015F3AB,
UPI0000E1F501,
UPI0000EE25A4,
UPI0000E1F500
EMBL:
BC067273,
AK222852,
BC001384,
AC012454,
AK302236,
AF130096,
CH471053,
AF132955,
AF161450,
AK001047,
AK001772,
AK295257,
AK289451,
AC016753,
AF353989,
AK056334
Ensembl:
ENSG00000168883
KO:
hsa:10713
|
| Nucleutide sequences |
EMBL-CDS:
AAH67273.1,
AAH01384.2,
AAD27730.1,
EAW99493.1,
AAK49524.1,
BAD96572.1,
AAF29010.1,
AAG35521.1,
BAF82140.1,
BAG50852.1,
EAW99494.1,
EAW99492.1,
BAG58246.1,
EAW99490.1,
BAH13655.1,
BAG50973.1,
BAG51679.1,
EAW99491.1
Gene_ORFName:
CGI-21,
PRO2855,
HSPC332,
hCG_34614
Ensembl_TRS:
ENST00000409470,
ENST00000323701,
ENST00000450066,
ENST00000409766,
ENST00000613444
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000396133,
ENSP00000312981,
ENSP00000386803,
ENSP00000386864,
ENSP00000484024
RefSeq:
XP_011530789.1,
NP_006581.2,
XP_011530790.1,
XP_006711985.1,
XP_006711986.1,
NP_001243655.1,
XP_016858671.1,
NP_001243656.1,
NP_001243657.1,
NP_001243654.1
|
| Others |
UniRef100:
UniRef100_B3KPG7,
UniRef100_Q53GS9,
UniRef100_B3KMG1,
UniRef100_B7Z7L9,
UniRef100_A0A087X1B2
UniRef90:
UniRef90_B3KPG7,
UniRef90_B3KMG1,
UniRef90_Q53GS9,
UniRef90_G3WU01
UniRef50:
UniRef50_A0A183CBL4,
UniRef50_Q53GS9,
UniRef50_G3WU01
UniGene:
Hs.654745
CCDS:
CCDS58716.1,
CCDS58717.1,
CCDS33234.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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