| Type | Description |
|---|---|
| Definition | malic enzyme 2, NAD(+)-dependent, mitochondrial |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 10:40:00 | deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer | 28099419 |
| 2013-02-16 10:26:00 | p53 represses the expression of the tricarboxylic-acid-cycle-associated malic enzymes ME1 and ME2 in human and mouse cells | 23334421 |
| 2010-01-21 00:00:00 | Me2 activity in Islet of Langerhans cells was measured by a spectrophotometric enzyme assay by utilizing the distinct kinetic properties of Me2. | 19691144 |
| Type | IDs |
|---|---|
| Synonymous | AW120568, D030040L20Rik, NAD-ME |
| Gene |
UniProtKB-ID:
MAOM_MOUSE
UniprotKB:
Q99KE1
UniParc:
UPI00000223A5
EMBL:
AK171157,
AK156403,
AK050980,
BC004709,
AK050933,
AK042289
Ensembl:
ENSMUSG00000024556
KO:
mmu:107029
|
| Nucleutide sequences |
EMBL-CDS:
BAE33701.1,
AAH04709.1,
BAC31216.1,
BAC34467.1,
BAE42281.1,
BAC34483.1
Ensembl_TRS:
ENSMUST00000025439
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025439
RefSeq:
NP_663469.1,
XP_006525559.1,
XP_036016815.1
|
| Others |
UniRef100:
UniRef100_Q99KE1
UniRef90:
UniRef90_P23368
UniRef50:
UniRef50_P23368
UniGene:
Mm.36817
CCDS:
CCDS29339.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 30550785 |
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Cell Hyeonwoo Kim , Christiane D Wrann , Mark Jedrychowski , Sara Vidoni , Yukiko Kitase , Kenichi Nagano , Chenhe Zhou , Joshua Chou , Virginia-Jeni A Parkman , Scott J Novick , Timothy S Strutzenberg , Bruce D Pascal , Phuong T Le , Daniel J Brooks , Alexander M Roche , Kaitlyn K Gerber , Laura Mattheis , Wenjing Chen , Hua Tu , Mary L Bouxsein , Patrick R Griffin , Roland Baron , Clifford J Rosen , Lynda F Bonewald , Bruce M Spiegelman |
2018-12-13 | - |
| 28099419 |
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature Prasenjit Dey , Joelle Baddour , Florian Muller , Chia Chin Wu , Huamin Wang , Wen-Ting Liao , Zangdao Lan , Alina Chen , Tony Gutschner , Yaan Kang , Jason Fleming , Nikunj Satani , Di Zhao , Abhinav Achreja , Lifeng Yang , Jiyoon Lee , Edward Chang , Giannicola Genovese , Andrea Viale , Haoqiang Ying , Giulio Draetta , Anirban Maitra , Y Alan Wang , Deepak Nagrath , Ronald A DePinho |
2017-02-02 | - |
| 23334421 |
Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence. Nature Peng Jiang , Wenjing Du , Anthony Mancuso , Kathryn E Wellen , Xiaolu Yang |
2013-01-31 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 21386911 |
PLoS ONE Rathi D Thiagarajan , Kylie M Georgas , Bree A Rumballe , Emmanuelle Lesieur , Han Sheng Chiu , Darrin Taylor , Dave T P Tang , Sean M Grimmond , Melissa H Little |
2011-01-01 |
1110002E22Rik,
Emilin1,
Itga9,
Smek2,
Slc17a3,
Gpsm3,
Me2,
Kazald1,
Aldh1l1,
Ccdc86,
Mybpc1,
Npy,
Slc18a1,
Ugt2b37,
Foxp2,
Ace,
Ehbp1l1,
Slc13a3,
Adcy8,
Ambp,
Acsm1,
Apoa4,
Nr2f2,
Synpo2,
Bmp2,
C2,
Cacnb4,
Capg,
Casp4,
Entpd5,
Cdh11,
Cideb,
Col3a1,
Col9a1,
Csrp1,
Cyp1b1,
Cyp4a10,
Dkk1,
Dpep1,
S1pr3,
Eya1,
F10,
Fbp2,
Fbp1,
Slc6a13,
Gpd1,
Gnb4,
Gng2,
Gpm6b,
Gria4,
Gk,
Hdc,
Hhex,
Hoxa10,
Hpgd,
Hpn,
Elavl1,
Elavl4,
Igf1,
Jag1,
Napsa,
Khsrp,
Aff3,
Lgals1,
Lhx1,
Stard4,
Rbm39,
Ly86,
Edaradd,
Kitl,
Mlf1,
Nxph1,
Slc22a6,
Pdgfra,
Pgf,
Prlr,
Pipox,
Ptn,
Ttc36,
Rem1,
Rgs5,
Nr1h4,
Scnn1b,
Sord,
Sema3b,
Slc23a1,
Slc3a1,
Serpini1,
Stc2,
Clic6,
Tcn2,
Tdrd5,
Rassf2,
Mfsd4b1,
BC089597,
Myo15b,
Serpina10,
Tgfb1i1,
Tgfbi
|
| 19691144 |
Arch. Biochem. Biophys. Michael J MacDonald , Melissa J Longacre , Mindy A Kendrick |
2009-08-15 | - |
| 19521500 |
PLoS Genet Stephen N Sansom , Dean S Griffiths , Andrea Faedo , Dirk-Jan Kleinjan , Youlin Ruan , James Smith , Veronica van Heyningen , John L Rubenstein , Frederick J Livesey |
2009-06-01 | - |
| 18614015 |
A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha |
2008-07-11 |
Acacb,
Hscb,
Gadd45gip1,
Lars2,
Acad11,
Chchd10,
Nt5dc3,
Slc25a41,
Nt5m,
Cyp27a1,
Acly,
Ndufb11,
Gldc,
Rexo2,
Rars,
Aldh6a1,
Slc25a47,
Rdh14,
Ppif,
Ldhal6b,
Me2,
Glyat,
Slc25a45,
Acaca,
Nt5c3,
Mrpl10,
Mrpl41,
Mrpl30,
Aldh1l1,
Mthfs,
Shmt2,
Atic,
Mthfd1,
Mat2b,
Fam210a,
Gpt2,
Lyrm2,
Rdh13,
Mtrf1l,
Atad3a,
Rars2,
Sccpdh,
Me3,
Maob,
Dut,
Cyp11b1,
Fdps,
Akr7a5,
Msra,
Krt5,
Cox6b1,
Qdpr,
Acat1,
Acat2,
Aldh7a1,
Pcca,
Etfb,
Etfa,
Nudt19,
Acadl,
Acadm,
Acadvl,
Acaa1a,
Acads,
Aco1,
Aco2,
Prosc,
Afg3l1,
Adsl,
Agxt,
Ak2,
Ak4,
Akap1,
Alas1,
Alas2,
Abcd1,
Aldh2,
Aldh3a2,
Gfer,
Acsm1,
Slc25a4,
Slc25a5,
Prdx3,
Prdx6,
Mrps2,
Arg2,
Rhoa,
Atp5a1,
Atp5b,
Atp5c1,
Atp5f1,
Atp5g1,
Atp5j,
Atp5k,
Atpif1,
Auh,
Akr1b7,
Bad,
Bak1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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