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107 ADCY1

107

ADCY1

adenylate cyclase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition adenylate cyclase 1

研究结论

Date Results Publications
2020-01-18 11:30:00 Mechanistic investigations identified adenylate cyclase 1 (ADCY1) as a direct target of miR-23a-3p in mucosal melanoma, and knockdown of ADCY1 recapitulated all the phenotypic characteristics of miR-23a-3p overexpression. 30867808
2017-11-25 15:28:00 data indicate that ST034307 is a selective small-molecule inhibitor of AC1 and suggest that selective AC1 inhibitors may be useful for managing pain. 28223412
2017-09-30 13:38:00 Data show that the adenylate cyclase (AC) pathway as genes relating to the antitumor activity of xanthohumol (XN) against tumor cells, and the pathway regulates various cellular functions via activating protein kinase A phosphorylation. 28122154
2016-10-15 15:17:00 Maps to 7p14.1-q11.22 between D7S2209 and marker D7S2435, maximum Lod score 5 for D7S1818. 15583425
2015-11-07 11:13:00 STC1 interferes with CALCRL signaling during osteoblastogenesis via adenylate cyclase inhibition. 25591908

名称对应

Type IDs
Synonymous AC1, DFNB44
Gene
UniProtKB-ID: ADCY1_HUMAN, C9J1J0_HUMAN
UniprotKB: Q08828, C9J1J0
UniParc: UPI0000199C4A, UPI0000D4A718
EMBL: AC069008, CH236960, L05500, CH471128, AC091439
Ensembl: ENSG00000164742
KO: hsa:107
Nucleutide sequences
EMBL-CDS: EAL23741.1, AAA02907.1, AAS07467.1, EAW61047.1
Gene_ORFName: hCG_19245
Ensembl_TRS: ENST00000297323, ENST00000432715, ENST00000621543
Protein sequencees
Ensembl_PRO: ENSP00000297323, ENSP00000479770, ENSP00000392721
RefSeq: NP_066939.1, XP_005249641.1, XP_005249642.1, NP_001268697.1
Others
UniRef100: UniRef100_C9J1J0, UniRef100_Q08828
UniRef90: UniRef90_O88444, UniRef90_C9J1J0
UniRef50: UniRef50_O88444, UniRef50_A0A672NPK7
UniGene: Hs.192215
CCDS: CCDS34631.1

全选

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