| Type | Description |
|---|---|
| Definition | chaperonin containing TCP1 subunit 8 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-13 11:29:00 | Study demonstrated that CCT8 expression is widely upregulated in esophageal squamous cell carcinoma (ESCC), and enhanced the migration and invasion of ESCC cells, indicating that ectopic CCT8 expression contributes to the highly aggressive nature of ESCC probably by increasing alpha-actin and beta-tubulin expression. | 29620162 |
| 2018-09-01 11:57:00 | Ectopic expression of CCT8 also ameliorates the age-associated demise of proteostasis and corrects proteostatic deficiencies in worm models of Huntington's disease. | 27892468 |
| 2017-02-18 10:58:00 | data suggest that the GRP94/CCT8/c-Jun/EMT signaling cascade might be a new therapeutic target for HCC | 26718209 |
| 2016-09-10 12:00:00 | showed that high CCT8 protein expression might be related to poor outcome of glioma | 26304164 |
| Type | IDs |
|---|---|
| Synonymous | C21orf112, Cctq, D21S246, PRED71 |
| Gene |
UniProtKB-ID:
TCPQ_HUMAN,
Q7Z759_HUMAN
UniprotKB:
P50990,
Q7Z759
UniParc:
UPI00001A3E65,
UPI000022B619,
UPI0000136B0D,
UPI00017A7721
EMBL:
CH471079,
BC012584,
D13627,
AK293705,
Z37163,
D42052,
BC095470,
AL163249,
AK298801,
BC072001,
AF129075
Ensembl:
ENSG00000156261
KO:
hsa:10694
|
| Nucleutide sequences |
EMBL-CDS:
BAA02792.2,
CAB90433.1,
BAA07652.1,
BAG57138.1,
AAH95470.1,
BAG60936.1,
CAA85520.1,
AAH72001.1,
AAH12584.1,
EAX09926.1
Gene_ORFName:
hCG_1810843
Ensembl_TRS:
ENST00000286788,
ENST00000540844,
ENST00000626972
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000286788,
ENSP00000486921,
ENSP00000442730
RefSeq:
NP_001269837.1,
NP_006576.2,
NP_001269836.1,
NP_001269838.1
|
| Others |
UniRef100:
UniRef100_P50990
UniRef90:
UniRef90_P50990
UniRef50:
UniRef50_P50990
UniGene:
Hs.125113
CCDS:
CCDS68181.1,
CCDS68180.1,
CCDS33528.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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