| Type | Description |
|---|---|
| Definition | G protein subunit alpha 13 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:09:00 | Galphas directly drives PDZ-RhoGEF signaling to Cdc42. | 33023908 |
| 2021-01-23 13:02:00 | G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3. | 32778842 |
| 2020-06-13 12:25:00 | these findings suggest that GNA13 drives CXCL5 expression by transactivating NF-kappaB in a Rho-dependent manner in prostate cancer cells. | 31636124 |
| 2020-01-25 14:20:00 | Signaling mechanisms and physiological functions of G-protein Galpha13 in blood vessel formation, bone homeostasis, and cancer. | 30345641 |
| 2019-11-09 12:41:00 | Results found that increased expression levels of GNA13 promoted cell growth, migration, invasion, and epithelial-mesenchymal transition, whereas GNA13 silencing abrogated these malignant phenotypes. In addition, overexpressing GNA13 in cancer cells increased the levels of the chemokines CXCL1, CXCL2, and CXCL4 via NF-kB signaling pathway, which contributed to colorectal cancer (CRC) proliferation and colony formation. | 30267476 |
| Type | IDs |
|---|---|
| Synonymous | G13 |
| Gene |
UniProtKB-ID:
GNA13_HUMAN,
A0A024R8M0_HUMAN
UniprotKB:
Q14344,
A0A024R8M0
UniParc:
UPI0000073EBA,
UPI0002065AF0
EMBL:
BC036756,
CH471099,
AC037487,
AK313672,
AK302400,
AF493902,
L22075
Ensembl:
ENSG00000120063
KO:
hsa:10672
|
| Nucleutide sequences |
EMBL-CDS:
BAH13696.1,
AAH36756.1,
EAW88993.1,
AAM12616.1,
AAA74235.1,
BAG36424.1,
EAW88995.1
Gene_ORFName:
hCG_1818067
Ensembl_TRS:
ENST00000439174,
ENST00000541118
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000439647,
ENSP00000400717
RefSeq:
NP_001269354.1,
NP_006563.2,
XP_011522504.1
|
| Others |
UniRef100:
UniRef100_Q14344
UniRef90:
UniRef90_Q14344
UniRef50:
UniRef50_Q14344
UniGene:
Hs.515018
CCDS:
CCDS62302.1,
CCDS11661.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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