| Type | Description |
|---|---|
| Definition | phosphomevalonate kinase |
| Date | Results | Publications |
|---|---|---|
| 2017-03-11 10:11:00 | Data indicate that exome sequencing revealed disseminated superficial porokeratosis (DSP)-associated mutations in phosphomevalonate kinase gene (PMVK). | 27052676 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | 20628086 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| 2010-01-21 00:00:00 | found an exclusive cytosolic localization of both endogenously expressed PMVK(in human fibroblasts, human liver, and HEK293 cells) and overexpressed PMVK. No indication of a peroxisomal localization was obtained. | 14729858 |
| 2010-01-21 00:00:00 | Binding of mevalonate 5-phosphate causes the phosphomevalonate kinase structure to compress (tau(c) = 13.5 nsec), whereas subsequent binding of Mg-ADP opens the structure up (tau(c) = 15.6 nsec). | 18798562 |
| Type | IDs |
|---|---|
| Synonymous | HUMPMKI, PMK, PMKA, PMKASE, POROK1 |
| Gene |
UniProtKB-ID:
PMVK_HUMAN,
Q6FGV9_HUMAN
UniprotKB:
Q15126,
Q6FGV9
UniParc:
UPI000013E263
EMBL:
BC007694,
AF026069,
L77213,
CH471121,
CR541998,
HM005718,
BT019976,
AK312803,
BC006089
Ensembl:
ENSG00000163344
KO:
hsa:10654
|
| Nucleutide sequences |
EMBL-CDS:
AAH07694.1,
AAC60791.1,
AAH06089.1,
AAC37593.1,
AAV38779.1,
EAW53178.1,
BAG35661.1,
CAG46795.1,
AEE61315.1,
EAW53177.1
Gene_ORFName:
hCG_1739272
Ensembl_TRS:
ENST00000368467
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357452
RefSeq:
NP_001309940.1,
NP_001335625.1,
NP_001309941.1,
NP_006547.1
|
| Others |
UniRef100:
UniRef100_Q15126
UniRef90:
UniRef90_Q15126
UniRef50:
UniRef50_Q15126
UniGene:
Hs.30954
CCDS:
CCDS1073.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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