Type | Description |
---|---|
Definition | protein kinase domain containing, cytoplasmic |
Date | Results | Publications |
---|---|---|
2020-07-18 11:18:00 | Taken together, these results suggest that Vlk may function as a signaling regulator in extracellular space to modulate the Hedgehog pathway | 31845979 |
2015-01-31 11:37:00 | Study shows that VLK, a putative protein kinase previously shown to be essential in embryonic development, is a secreted protein kinase, with preference for tyrosine, that phosphorylates a broad range of secreted and endoplasmic reticulum-resident substrate proteins. | 25171405 |
2013-11-16 10:19:00 | VLK plays a role in the Indian hedgehog /GLI3 interactions and that Vlk and Gli3 cooperate to regulate long bone development | 23792766 |
2011-12-17 10:38:00 | Adtk1 null mutants are smaller and present short limbs due to decreased mineralization, suggesting a potential role in chondrogenesis during limb development. | 21553379 |
2010-01-21 00:00:00 | Vlk is a novel vertebrate-specific PK that is involved in the regulation of the rate of protein export from the Golgi, thereby playing an important role in the formation of functional stroma by mesenchymal cells. | 19465597 |
Type | IDs |
---|---|
Synonymous | AI115348, AW548124, Adtk1, ESTM17, MAd1, Sgk493, Vlk, X83346 |
Gene |
UniProtKB-ID:
PKDCC_MOUSE
UniprotKB:
Q5RJI4
UniParc:
UPI0001C67AA4,
UPI000181BFC4
EMBL:
AK133913,
AB381893,
BC022157,
AB436780,
BC086639
Ensembl:
ENSMUSG00000024247
KO:
mmu:106522
|
Nucleutide sequences |
EMBL-CDS:
BAE21924.1,
AAH22157.1,
AAH86639.1,
BAG82823.1,
BAH66379.1
Ensembl_TRS:
ENSMUST00000170794
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129238
RefSeq:
XP_011244536.1,
NP_598878.2
|
Others |
UniRef100:
UniRef100_Q5RJI4
UniRef90:
UniRef90_Q5RJI4
UniRef50:
UniRef50_Q5RJI4
UniGene:
Mm.311974
CCDS:
CCDS28994.2
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
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Refseq |
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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