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106522 Pkdcc

106522

Pkdcc

protein kinase domain containing, cytoplasmic

protein-coding

Mus musculus

基因描述

Type Description
Definition protein kinase domain containing, cytoplasmic

研究结论

Date Results Publications
2020-07-18 11:18:00 Taken together, these results suggest that Vlk may function as a signaling regulator in extracellular space to modulate the Hedgehog pathway 31845979
2015-01-31 11:37:00 Study shows that VLK, a putative protein kinase previously shown to be essential in embryonic development, is a secreted protein kinase, with preference for tyrosine, that phosphorylates a broad range of secreted and endoplasmic reticulum-resident substrate proteins. 25171405
2013-11-16 10:19:00 VLK plays a role in the Indian hedgehog /GLI3 interactions and that Vlk and Gli3 cooperate to regulate long bone development 23792766
2011-12-17 10:38:00 Adtk1 null mutants are smaller and present short limbs due to decreased mineralization, suggesting a potential role in chondrogenesis during limb development. 21553379
2010-01-21 00:00:00 Vlk is a novel vertebrate-specific PK that is involved in the regulation of the rate of protein export from the Golgi, thereby playing an important role in the formation of functional stroma by mesenchymal cells. 19465597

名称对应

Type IDs
Synonymous AI115348, AW548124, Adtk1, ESTM17, MAd1, Sgk493, Vlk, X83346
Gene
UniProtKB-ID: PKDCC_MOUSE
UniprotKB: Q5RJI4
UniParc: UPI0001C67AA4, UPI000181BFC4
EMBL: AK133913, AB381893, BC022157, AB436780, BC086639
Ensembl: ENSMUSG00000024247
KO: mmu:106522
Nucleutide sequences
EMBL-CDS: BAE21924.1, AAH22157.1, AAH86639.1, BAG82823.1, BAH66379.1
Ensembl_TRS: ENSMUST00000170794
Protein sequencees
Ensembl_PRO: ENSMUSP00000129238
RefSeq: XP_011244536.1, NP_598878.2
Others
UniRef100: UniRef100_Q5RJI4
UniRef90: UniRef90_Q5RJI4
UniRef50: UniRef50_Q5RJI4
UniGene: Mm.311974
CCDS: CCDS28994.2

全选

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研究热度

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