| Type | Description |
|---|---|
| Definition | solute carrier family 51, alpha subunit |
| Date | Results | Publications |
|---|---|---|
| 2017-07-15 10:12:00 | Data suggest that transport of bile acid taurocholate is retained when OstB (organic solute transporter beta subunit) is truncated to contain only the transmembrane domain with 15 additional residues on each side and co-expressed with intact OstA; shorter fragments of OstB are inactive. | 28455390 |
| 2014-04-26 12:59:00 | These findings indicate that loss of OSTalpha protects against age-related weight gain and insulin resistance. | 24381083 |
| 2013-11-16 11:12:00 | Ileal FGF15 expression was directly correlated with plasma cholesterol levels and aortic cholesterol content. In contrast, plasma and hepatic cholesterol levels and atherosclerosis development were not reduced in apoE(-/-) mice deficient in Ostalpha. | 23880190 |
| 2012-12-08 10:07:00 | Total ileal FGF15 expression was elevated almost 20-fold in Ostalpha(-/-) mice as a result of increased villus epithelial cell number and ileocyte FGF15 protein expression | 22542490 |
| 2011-10-29 10:21:00 | Inactivation of FXR largely unmasked the bile acid malabsorption phenotype and corrected the bile acid homeostasis defect in Ostalpha null mice. | 21691100 |
| Type | IDs |
|---|---|
| Synonymous | AV001382, AW261577, D630035O19Rik, OSTalpha, Osta |
| Gene |
UniProtKB-ID:
OSTA_MOUSE
UniprotKB:
Q8R000
UniParc:
UPI0000027B0F
EMBL:
BC024441,
AK052725,
BC025912,
AK147155,
BC031178
Ensembl:
ENSMUSG00000035699
KO:
mmu:106407
|
| Nucleutide sequences |
EMBL-CDS:
AAH25912.1,
AAH24441.1,
AAH31178.1,
BAC35116.1,
BAE27722.1
Ensembl_TRS:
ENSMUST00000042042
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000046286
RefSeq:
NP_666044.1
|
| Others |
UniRef100:
UniRef100_Q8R000
UniRef90:
UniRef90_Q8R000
UniRef50:
UniRef50_Q8R000
UniGene:
Mm.476915
CCDS:
CCDS28121.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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