| Type | Description |
|---|---|
| Definition | centromere protein E |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:24:00 | Reduced expression of CENP-E contributes to the development of hepatocellular carcinoma and is associated with adverse clinical features. | 31881483 |
| 2020-07-04 12:31:00 | These results collectively suggest a tension-independent mechanism to reduce Aurora B-mediated phosphorylation of outer kinetochore components in response to microtubule capture by CENP-E. | 31122175 |
| 2019-12-21 11:56:00 | Study revealed that CENPE is highly expressed in lung adenocarcinoma (LUAD) tissues. In addition, FOXM1 is correlated with the expression of CENE and is associated with the proliferation of lung cancer cells. FOXM1 binds directly to the promoter region of CENPE. Therefore, the current data indicate that CENPE can promote the proliferation of LUAD cells and is directly regulated by FOXM1. | 31115500 |
| 2019-11-02 12:21:00 | The methylation status of cg27443373 and cg24651824 might play a critical role in modulating CENPE expression. | 30716092 |
| 2019-02-23 10:57:00 | Study demonstrates that KNL1 acts as a receptor of linear ubiquitin chains to anchor CENP-E at attached kinetochores. Thus, linear ubiquitin chains constitute a critical mechanism for chromosome congression and alignment by coupling the dynamic kinetochore microtubule motor CENP-E to the static one, the KMN network. | 30655516 |
| Type | IDs |
|---|---|
| Synonymous | CENP-E, KIF10, MCPH13, PPP1R61 |
| Gene |
UniProtKB-ID:
CENPE_HUMAN
UniprotKB:
Q02224
UniParc:
UPI000020B28A,
UPI00015D773C
EMBL:
AB209996,
CH471057,
AK290362,
AC079919,
Z15005
Ensembl:
ENSG00000138778
KO:
hsa:1062
|
| Nucleutide sequences |
EMBL-CDS:
BAE06078.1,
CAA78727.1,
BAF83051.1,
EAX06171.1
Ensembl_TRS:
ENST00000380026,
ENST00000265148
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369365,
ENSP00000265148
RefSeq:
XP_016863148.1,
XP_011529846.1,
XP_011529851.1,
XP_011529849.1,
XP_011529850.1,
XP_011529847.1,
NP_001804.2,
XP_011529848.1,
NP_001273663.1
|
| Others |
UniRef100:
UniRef100_Q02224
UniRef90:
UniRef90_Q02224
UniRef50:
UniRef50_Q02224
UniGene:
Hs.75573
CCDS:
CCDS34042.1,
CCDS68768.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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