| Type | Description |
|---|---|
| Definition | HEXIM P-TEFb complex subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:12:00 | Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer. | 31776402 |
| 2020-09-26 13:02:00 | HEXIM1 Diffusion in the Nucleus Is Regulated by Its Interactions with Both 7SK and P-TEFb. | 31590891 |
| 2020-05-23 12:33:00 | HMBA and 4a1 induce HEXIM1 expression by inhibiting KDM5B. Upregulation of HEXIM1 expression levels plays a critical role in the inhibition of proliferation of breast cancer cells using KDM5B inhibitors. | 31805991 |
| 2020-03-21 12:03:00 | Structural transitions in the RNA 7SK 5' hairpin and their effect on HEXIM binding have been reported. | 31732748 |
| 2019-12-14 11:29:00 | Both HEXIM1 and RAD51 promote BET inhibitor-induced fork slowing but also prevent a DNA damage response. | 30463005 |
| Type | IDs |
|---|---|
| Synonymous | CLP1, EDG1, HIS1, MAQ1 |
| Gene |
UniProtKB-ID:
HEXI1_HUMAN
UniprotKB:
O94992
UniParc:
UPI000006E405
EMBL:
BC006460,
AB021179,
AK313557
Ensembl:
ENSG00000186834
KO:
hsa:10614
|
| Nucleutide sequences |
EMBL-CDS:
BAG36332.1,
BAA36166.1,
AAH06460.1
Ensembl_TRS:
ENST00000332499
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000328773
RefSeq:
NP_006451.1
|
| Others |
UniRef100:
UniRef100_O94992
UniRef90:
UniRef90_O94992
UniRef50:
UniRef50_O94992
UniGene:
Hs.586945,
Hs.741758,
Hs.745252
CCDS:
CCDS11495.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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