| Type | Description |
|---|---|
| Definition | ER lipid raft associated 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:09:00 | Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease. | 32776921 |
| 2020-08-01 10:53:00 | erlin-1 protein is required early in the infection, downstream of cell entry and primary translation, specifically to initiate RNA replication, and later in the infection to support infectious virus production. This study identifies erlin-1 protein as an important cellular factor regulating HCV infection. | 31810281 |
| 2015-03-16 13:18:00 | Erlin-1 and the related erlin-2 were found to selectively bind cholesterol. Knockdown of the proteins by in cultured cells resulted in high levels of cholesterol and fatty acid biosynthesis in the presence of cholesterol sufficiency. | 24217618 |
| 2014-01-11 10:06:00 | Here we show that the multimeric ER proteins erlins-1 and -2 are additional sterol regulatory element binding protein regulators. | 24217618 |
| 2013-11-16 11:52:00 | Our findings suggest ERLIN1-CHUK-CWF19L1 variants are associated with early stage of fatty liver accumulation to hepatic inflammation. | 23477746 |
| Type | IDs |
|---|---|
| Synonymous | C10orf69, Erlin-1, KE04, KEO4, SPFH1, SPG62 |
| Gene |
UniProtKB-ID:
ERLN1_HUMAN
UniprotKB:
O75477
UniParc:
UPI0000155AF8
EMBL:
AF064093,
BC031791,
CH471066,
AK222480,
AL138921
Ensembl:
ENSG00000107566
KO:
hsa:10613
|
| Nucleutide sequences |
EMBL-CDS:
BAD96200.1,
AAC26658.1,
AAH31791.1,
EAW49846.1,
EAW49847.1
Ensembl_TRS:
ENST00000421367,
ENST00000407654
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000384900,
ENSP00000410964
RefSeq:
NP_001334788.1,
NP_001094096.1,
NP_006450.2,
NP_001334790.1,
NP_001334789.1,
NP_001334786.1,
NP_001334787.1,
NP_001334785.1
|
| Others |
UniRef100:
UniRef100_O75477
UniRef90:
UniRef90_O75477
UniRef50:
UniRef50_O75477
UniGene:
Hs.150087
CCDS:
CCDS7487.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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