| Type | Description |
|---|---|
| Definition | PDZ and LIM domain 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:41:00 | Mutations in PDLIM5 are rare in dilated cardiomyopathy but are emerging as potential disease modifiers. | 31880413 |
| 2021-02-06 13:58:00 | PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells. | 32737199 |
| 2020-09-05 13:54:00 | Novel polymorphisms in PDLIM3 and PDLIM5 gene encoding Z-line proteins increase risk of idiopathic dilated cardiomyopathy. | 31424159 |
| 2020-01-11 10:14:00 | Forces acting on integrins recruit Enigma family proteins (PDLIM5 AND PDLIM7) to trigger YAP activation during mechanotransduction. | 30404826 |
| 2018-10-27 12:17:00 | this study shows functional importance of PDLIM5 for proper kAE1 membrane residency, as a crucial linker between kidneyAE1 and actin cytoskeleton-associated proteins in polarized cells | 28045035 |
| Type | IDs |
|---|---|
| Synonymous | ENH, ENH1, L9, LIM |
| Gene |
UniProtKB-ID:
PDLI5_HUMAN,
B7Z481_HUMAN,
B7Z8X5_HUMAN,
A0A024RDE8_HUMAN
UniprotKB:
Q96HC4,
B7Z481,
B7Z8X5,
A0A024RDE8
UniParc:
UPI0000EE2C76,
UPI000013E231,
UPI00001401E8,
UPI0001914FE9,
UPI00004F77EB,
UPI0001D3B60C,
UPI00001401C7,
UPI0001915455,
UPI00001401DD,
UPI0000071F66
EMBL:
CR610626,
AC108067,
AC093778,
CH471057,
AK291898,
AL833438,
BC008741,
BT007328,
BC017902,
AK291624,
AF061258,
AY345240,
AY598328,
AC109925,
AK296980,
AK304125
Ensembl:
ENSG00000163110
KO:
hsa:10611
|
| Nucleutide sequences |
EMBL-CDS:
AAH17902.1,
BAF84313.1,
AAR09142.1,
BAF84587.1,
AAT06739.1,
AAC15767.1,
AAH08741.1,
EAX06054.1,
AAP35992.1,
BAH12467.1,
BAH14111.1,
EAX06057.1,
EAX06055.1
Gene_ORFName:
L9,
hCG_40208
Ensembl_TRS:
ENST00000380180,
ENST00000508216,
ENST00000542407,
ENST00000317968,
ENST00000503974,
ENST00000514743,
ENST00000318007,
ENST00000359265,
ENST00000615540
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000424297,
ENSP00000322021,
ENSP00000369527,
ENSP00000424360,
ENSP00000426804,
ENSP00000442187,
ENSP00000480359,
ENSP00000352210,
ENSP00000321746
RefSeq:
NP_001011513.4,
NP_001243357.2,
NP_006448.5,
NP_001243355.2,
NP_001011516.1,
NP_001243356.2,
NP_001243358.1,
NP_001011515.1,
NP_001243354.2
|
| Others |
UniRef100:
UniRef100_B7Z481,
UniRef100_Q96HC4,
UniRef100_A0A024RDE8,
UniRef100_B7Z8X5
UniRef90:
UniRef90_Q96HC4,
UniRef90_B7Z481,
UniRef90_B7Z8X5
UniRef50:
UniRef50_Q96HC4,
UniRef50_Q96HC4-4,
UniRef50_Q59FC9
UniGene:
Hs.480311,
Hs.732677
CCDS:
CCDS3641.1,
CCDS47104.1,
CCDS58915.1,
CCDS58917.1,
CCDS47102.1,
CCDS47103.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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