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10610 ST6GALNAC2

10610

ST6GALNAC2

ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

研究结论

Date Results Publications
2017-12-09 13:38:00 MicroRNAs miR-135b and miR-182 may reverse the resistance to 5-fluorouracil (5-FU) in colorectal cancer (CRC) cells by targeting ST6GALNAC2 via PI3K/AKT pathway, which render potential chemotherapy targets for the treatment of CRC. 28767179
2017-12-09 11:44:00 miR-182/-135b/ST6GALNAC2/PI3K/AKT axis could function as regulator of progression in colorectal cancer 29030743
2017-02-04 10:51:00 Study provides evidence that mutations in B3GNT2, B4GALT2, and ST6GALNAC2 underlie aberrant glycosylation, and contribute to the pathogenesis of molecular subsets of colon and other gastrointestinal malignancies. 27004849
2016-12-31 10:54:00 Results provide evidence that ST6GalNAcII activated the invasion in follicular thyroid cancer cells through regulating the activity of PI3K/Akt pathway. 26820593
2015-01-17 13:16:00 High expression level of ST6GalNAcII is associated with invasive phenotype of breast cancer. 24756995

名称对应

Type IDs
Synonymous SAITL1, SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM
Gene
UniProtKB-ID: SIA7B_HUMAN, A0A024R8M1_HUMAN
UniprotKB: Q9UJ37, A0A024R8M1
UniParc: UPI000000D98B
EMBL: U14550, CH471099, AJ251053, BT019972, BC040455
Ensembl: ENSG00000070731
KO: hsa:10610
Nucleutide sequences
EMBL-CDS: AAH40455.1, AAA52228.1, CAB61434.1, AAV38775.1, EAW89418.1, EAW89417.1
Gene_ORFName: hCG_30890
Ensembl_TRS: ENST00000225276
Protein sequencees
Ensembl_PRO: ENSP00000225276
RefSeq: XP_005257011.1, XP_024306307.1, NP_006447.2
Others
UniRef100: UniRef100_Q9UJ37
UniRef90: UniRef90_Q9UJ37
UniRef50: UniRef50_Q9UJ37
UniGene: Hs.592105
CCDS: CCDS11747.1

全选

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