| Type | Description |
|---|---|
| Definition | SH2B adaptor protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2013-04-13 11:33:00 | Studies indicate that insulin receptor (IR) and IGF Type 1 Receptor (IGFR) have been identified as important partners of Grb10/14 and SH2B1/B2 adaptors. | 23190452 |
| 2010-04-07 21:40:00 | Observational study of gene-disease association. (HuGE Navigator) | 20237496 |
| 2010-01-21 00:00:00 | We present here a novel stimulatory mechanism of Vav3 in which APS directly relieves the autoinhibitory CH domain and furthermore enhances its tyrosine phosphorylation by Lck. | 12400014 |
| 2010-01-21 00:00:00 | N-terminal residues distal to the phosphotyrosine directly contact residues of the four-helix bundle of the TKB domain of the adapter protein APS | 15737992 |
| 2008-03-13 09:01:00 | Observational study of gene-disease association. (HuGE Navigator) | 12101115 |
| Type | IDs |
|---|---|
| Synonymous | APS |
| Gene |
UniProtKB-ID:
SH2B2_HUMAN
UniprotKB:
O14492
UniParc:
UPI0000EE7EB0,
UPI000022D3DD
EMBL:
AC005088,
CH471197,
AC091390,
AB000520
Ensembl:
ENSG00000160999
KO:
hsa:10603
|
| Nucleutide sequences |
EMBL-CDS:
BAA22514.1,
EAW50232.1
Ensembl_TRS:
ENST00000536178
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000440273
RefSeq:
NP_001346157.1,
XP_005277032.1,
NP_001346160.1,
XP_005277033.1,
NP_001346159.1,
NP_001346158.1,
NP_066189.3
|
| Others |
UniRef100:
UniRef100_O14492
UniRef90:
UniRef90_O14492
UniRef50:
UniRef50_O14492
UniGene:
Hs.489448
CCDS:
CCDS78264.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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