| Type | Description |
|---|---|
| Definition | SHANK-associated RH domain interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:58:00 | A novel role for in amyloid-beta phagocytosis and inflammation by peripheral blood-derived macrophages in Alzheimer's disease. | 32165044 |
| 2020-09-12 16:03:00 | Keratinocyte-specific deletion of induces atopic dermatitis-like inflammation in mice. | 32687504 |
| 2020-09-12 11:05:00 | The sharpin may complex with both kindlin-1 and the integrin beta1 CT to restrict the talin head domain binding, thus inhibiting beta1-integrin activation. | 31429758 |
| 2020-06-06 11:30:00 | Fibroblasts derived from Sharpin(cpdm)Myd88(--) mice failed to provide protection against TNF-induced cell death. Sharpin(cpdm)Myd88(--) mice had reduced TNF production in their skin. | 30038386 |
| 2020-04-18 10:51:00 | a protein previously associated with increased cancer growth and metastasis, may also have important regulatory roles in controlling the tumor microenvironment | 30850498 |
| Type | IDs |
|---|---|
| Synonymous | 0610041B22Rik, AW121341, RBCKL1, SIPL1, cpdm |
| Gene |
UniProtKB-ID:
SHRPN_MOUSE
UniprotKB:
Q91WA6
UniParc:
UPI00001B6379,
UPI000002935E
EMBL:
AB052763,
BC016203,
BC055758
Ensembl:
ENSMUSG00000022552
KO:
mmu:106025
|
| Nucleutide sequences |
EMBL-CDS:
AAH55758.1,
BAC53796.1,
AAH16203.1
Ensembl_TRS:
ENSMUST00000023211
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023211
RefSeq:
NP_079616.2,
XP_006520326.1,
XP_011243700.1
|
| Others |
UniRef100:
UniRef100_Q91WA6
UniRef90:
UniRef90_Q91WA6
UniRef50:
UniRef50_Q91WA6
UniGene:
Mm.41463
CCDS:
CCDS37121.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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