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106021 Topors

106021

Topors

topoisomerase I binding, arginine/serine-rich

protein-coding

Mus musculus

基因描述

Type Description
Definition topoisomerase I binding, arginine/serine-rich

研究结论

Date Results Publications
2020-07-18 10:53:00 TOPORS regulates chromatin architecture partially by interacting with PML. 32113985
2013-03-09 10:25:00 Data suggest a mechanism for the inhibitory effects of Sdc-1 on cell growth that involves the interaction between the cytoplasmic domain of Sdc-1 and the SUMO-1 E3 ligase, Topors. 22912899
2010-06-28 11:58:00 These results indicate a unique role for Topors in the maintenance of genomic stability and pericentric heterochromatin, as well as in cellular sensitivity to histone deacetylase inhibitors. 20429939
2010-01-21 00:00:00 NKX3.1 can be ubiquitinated by TOPORS in vitro and in vivo, and overexpression of TOPORS leads to NKX3.1 proteasomal degradation in prostate cancer cells 18077445

名称对应

Type IDs
Synonymous AW105885, LUN, TP53BPL, p53BP3/LUN
Gene
UniProtKB-ID: TOPRS_MOUSE
UniprotKB: Q80Z37
UniParc: UPI0000002671
EMBL: AK143025, BC040797, AK140250, AK044564, AB104865, BC037141, AB072395, AK153743, AK134075
Ensembl: ENSMUSG00000036822
KO: mmu:106021
Nucleutide sequences
EMBL-CDS: AAH40797.1, BAE22003.1, BAC65157.1, BAE32164.1, AAH37141.1, BAE25253.1, BAC31981.2, BAE24298.1, BAB69457.1
Ensembl_TRS: ENSMUST00000042575
Protein sequencees
Ensembl_PRO: ENSMUSP00000046843
RefSeq: NP_598858.2, XP_036019455.1
Others
UniRef100: UniRef100_Q80Z37
UniRef90: UniRef90_Q80Z37
UniRef50: UniRef50_Q9NS56
UniGene: Mm.251548
CCDS: CCDS38710.1

全选

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研究热度

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