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10592 SMC2

10592

SMC2

structural maintenance of chromosomes 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition structural maintenance of chromosomes 2

研究结论

Date Results Publications
2020-08-22 15:31:00 Structural maintenance of chromosomes 2 is identified as an oncogene in bladder cancer in vitro and in vivo. 31986889
2020-02-22 11:06:00 Rs3818626 and rs9895829 were significantly associated with SMC2 and TP53 messenger RNA expression. 30794721
2016-05-14 10:07:00 SMC2 (or the condensin complex) is a novel molecular target for the treatment of MYCN-amplified neuroblastoma. 24553121
2016-04-23 10:26:00 analysis of functional differences of SMC2 and SMC4 hinge domain between condensins and cohesin in DNA recognition 26491021
2014-08-16 12:33:00 SMC2 gene is altered by both frameshift mutation and loss of expression in gastric and colorectal cancers, suggesting that SMC2 gene alterations might be involved in pathogenesis of these cancers 24483990

名称对应

Type IDs
Synonymous CAP-E, CAPE, SMC-2, SMC2L1
Gene
UniProtKB-ID: SMC2_HUMAN, B7ZLZ7_HUMAN, A8K984_HUMAN, Q05D74_HUMAN, Q7Z2X1_HUMAN, A0A024R158_HUMAN, Q05BV1_HUMAN, Q6IPS5_HUMAN, B3KMB1_HUMAN
UniprotKB: O95347, B7ZLZ7, A8K984, Q05D74, Q7Z2X1, A0A024R158, Q05BV1, Q6IPS5, B3KMB1
UniParc: UPI00015DA963, UPI0000D49E28, UPI000042518B, UPI000189A8EC, UPI000013DE44, UPI0000378317, UPI00001B2E3F, UPI000015F348, UPI0000D4971B
EMBL: AL833191, BC055081, AF092563, AK001485, AK292599, AF113673, BC144163, BN000163, AL354938, BC017845, CH471105, BC130385, BC071750, AL161791, BC032705
Ensembl: ENSG00000136824
KO: hsa:10592
Nucleutide sequences
EMBL-CDS: AAI30386.1, AAF29579.1, CAI46187.1, AAC72360.1, CAD89875.1, EAW58973.1, AAI44164.1, BAF85288.1, AAH17845.1, AAH55081.1, EAW58975.1, EAW58977.1, AAH32705.1, AAH71750.1, BAG50923.1
Gene_ORFName: PRO0324, hCG_27645
Ensembl_TRS: ENST00000374793, ENST00000374787, ENST00000286398
Protein sequencees
Ensembl_PRO: ENSP00000363919, ENSP00000363925, ENSP00000286398
RefSeq: XP_011516455.1, NP_001252531.1, NP_001036016.1, NP_006435.2, XP_011516453.1, XP_016869700.1, XP_011516451.1, NP_001036015.1, XP_016869696.1, XP_011516454.1, XP_016869701.1, XP_024303151.1, XP_016869698.1, XP_016869699.1, XP_011516450.1, XP_016869695.1, XP_006716996.1, XP_016869697.1, XP_011516452.1
Others
UniRef100: UniRef100_O95347, UniRef100_B3KMB1, UniRef100_Q6IPS5, UniRef100_Q7Z2X1, UniRef100_B7ZLZ7, UniRef100_Q05BV1, UniRef100_Q05D74, UniRef100_A8K984
UniRef90: UniRef90_A0A5N4E980, UniRef90_G1P283, UniRef90_Q6IPS5, UniRef90_Q7Z2X1, UniRef90_O95347
UniRef50: UniRef50_O95347, UniRef50_Q6IPS5, UniRef50_A0A6I8QAA7, UniRef50_Q7Z2X1
UniGene: Hs.119023
CCDS: CCDS35086.1

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