| Type | Description |
|---|---|
| Definition | thioredoxin reductase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 11:32:00 | The aim of the study was to investigate the association between rs5859 in Sep15, rs1139793 in TrxR2 polymorphisms with the risks of KBD and to detect the expression of AP-1 pathway. | 29653292 |
| 2018-10-27 10:29:00 | Based on recent research, it has been reported that the modulation of the Trx/TrxR system may be considered as a new target in the management of the metabolic syndrome, insulin resistance, and type 2 diabetes, as well as in the treatment of hypertension and atherosclerosis. In this review evidence about a possible role of this system as a marker of the metabolic syndrome is reported. [review] | 29327078 |
| 2017-07-01 12:19:00 | TrxR2 was overexpressed in non-small-cell lung cancer cells; our results suggest that TrxR2 acts as an oncogenic gene in the context of lung cancer progression | 28414076 |
| 2017-06-10 12:02:00 | p53R2 acts as a positive regulator of TrxR2 activity in mitochondria both under normal physiological conditions and during the cellular response to DNA damage | 27866984 |
| 2017-05-13 10:56:00 | TrxR2 deficiency-induced impaired proliferation and death of chondrocytes may be the pathological mechanism of the osteoarthropathy due to Selenium deficiency. | 27107686 |
| Type | IDs |
|---|---|
| Synonymous | GCCD5, SELZ, TR, TR-BETA, TR3, TRXR2 |
| Gene |
UniProtKB-ID:
TRXR2_HUMAN,
E7EWK1_HUMAN
UniprotKB:
Q9NNW7,
E7EWK1
UniParc:
UPI0001642907,
UPI0001AE62D1,
UPI0000167BDD,
UPI0000167BA6,
UPI0001642906
EMBL:
AC000078,
AC000090,
AF106697,
AF166127,
BC007489,
AC000080,
AF201385,
AF166126,
AF044212,
AB019695,
AF171054,
AB019694
Ensembl:
ENSG00000184470
KO:
hsa:10587
|
| Nucleutide sequences |
EMBL-CDS:
AAF21431.1,
BAA77602.2,
AAD51324.1,
AAG47635.1,
BAA77601.2,
AAH07489.3,
AAF21432.1,
AAD25167.1,
AAD19597.1
Ensembl_TRS:
ENST00000542719,
ENST00000400521,
ENST00000334363
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000485128,
ENSP00000383365,
ENSP00000334451
RefSeq:
NP_001269441.1,
NP_001339231.1,
NP_001339230.1,
NP_001339232.1,
NP_001339229.1,
NP_006431.2
|
| Others |
UniRef100:
UniRef100_E7EWK1,
UniRef100_Q9NNW7
UniRef90:
UniRef90_Q9NNW7,
UniRef90_A0A2I2ZNN4
UniRef50:
UniRef50_A0A0Q3UQ92,
UniRef50_Q9Z0J5
UniGene:
Hs.443430
CCDS:
CCDS86998.1,
CCDS42981.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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