| Type | Description |
|---|---|
| Definition | Mdm2, transformed 3T3 cell double minute p53 binding protein |
| Date | Results | Publications |
|---|---|---|
| 2017-11-18 11:38:00 | Mtbp haploinsufficiency significantly increased longevity and maximal survival in mice. Reduced levels of Mtbp did not alter locomotor activity, litter size, or body size, but Mtbp heterozygous mice did exhibit elevated markers of metabolism, particularly in the liver. Mtbp(+/-) mice also had a significant delay in spontaneous cancer development | 27803394 |
| 2010-10-04 12:33:00 | Mtbp functioned independent of Mdm2 and was a limiting factor for the proliferative and transforming functions of Myc. Thus, Mtbp is a previously unrecognized regulator of Myc-induced tumorigenesis. | 20305689 |
| 2010-01-21 00:00:00 | Mtbp haploinsufficiency in mice increases tumor metastasis | 17906694 |
| Type | IDs |
|---|---|
| Synonymous | AI429604, MDM2BP |
| Gene |
UniProtKB-ID:
MTBP_MOUSE
UniprotKB:
Q8BJS8
UniParc:
UPI00000EAAFD,
UPI00000EAB08,
UPI0000021EB5
EMBL:
BC052197,
AK080036,
AK088652,
AK088549,
AJ278508,
AK133855,
BC005500
Ensembl:
ENSMUSG00000022369
KO:
mmu:105837
|
| Nucleutide sequences |
EMBL-CDS:
BAC37810.1,
BAC40479.1,
BAC40418.1,
BAE21889.1,
AAH52197.1,
CAC07970.1,
AAH05500.1
Ensembl_TRS:
ENSMUST00000169667,
ENSMUST00000170046,
ENSMUST00000022998
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000129396,
ENSMUSP00000022998,
ENSMUSP00000128615
RefSeq:
XP_011243696.1,
XP_006520313.1,
NP_001161722.1,
XP_017171850.1,
XP_017171849.1,
NP_598853.3
|
| Others |
UniRef100:
UniRef100_Q8BJS8
UniRef90:
UniRef90_Q8BJS8
UniRef50:
UniRef50_Q8BJS8
UniGene:
Mm.390829
CCDS:
CCDS49609.1,
CCDS27478.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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