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10549 PRDX4

10549

PRDX4

peroxiredoxin 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition peroxiredoxin 4

研究结论

Date Results Publications
2021-02-13 13:27:00 [Differential expression of PRDX4 in alveolar macrophages of patients with silicosis]. 33535333
2020-06-27 10:36:00 Hepatocellular carcinoma (HCC) tumors with low expression of PRDX4 had higher levels, malignancy, and associated with reduced overall survival. In HCC cell lines, its knockdown led to increased intracellular duanyu1670 level and suppressed cell proliferation, inducing cell death. These results indicate that PRDX4 has an inhibitory effect in the initiation of HCC, but a dual (inhibitory or promoting) role in the progression. 29687726
2020-05-02 10:57:00 The PRDX4 expression and EGFR mutation status were significantly associated with the prognosis of patients with stage I lung adenocarcinoma, and EGFR mutations affected the role of PRDX4 in the proliferation of lung adenocarcinoma cells. 31588184
2020-04-11 12:38:00 PRDX4 reduces anoikis and promotes tumorigenesis and metastasis of hepatocellular carcinoma cells through stabilization of the beta-catenin protein and upregulation of ID2. 31256347
2020-01-11 12:17:00 n this article, the characteristics of peroxiredoxin 4 in physiological functions and the cancer-related research progress of mammalian peroxiredoxin 4 is reviewed. We believe that peroxiredoxin 4 has the potential of serving as a novel target for multiple cancers. 31311441

名称对应

Type IDs
Synonymous AOE37-2, AOE372, HEL-S-97n, PRX-4
Gene
UniProtKB-ID: PRDX4_HUMAN, V9HW63_HUMAN
UniprotKB: Q13162, V9HW63
UniParc: UPI00001314E8
EMBL: CR541705, FJ224297, BC003609, BC016770, CR541668, U25182, CH471074, BC007107
Ensembl: ENSG00000123131
KO: hsa:10549
Nucleutide sequences
EMBL-CDS: AAH07107.1, AAB95175.1, AAH03609.1, CAG46506.1, AAH16770.1, CAG46469.1, EAW98996.1, ACI45989.1
Gene_ORFName: hCG_17636
Ensembl_TRS: ENST00000379341
Protein sequencees
Ensembl_PRO: ENSP00000368646
RefSeq: NP_006397.1
Others
UniRef100: UniRef100_Q13162
UniRef90: UniRef90_Q13162
UniRef50: UniRef50_Q13162
UniGene: Hs.83383
CCDS: CCDS14206.1

全选

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