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10542 LAMTOR5

10542

LAMTOR5

late endosomal/lysosomal adaptor, MAPK and MTOR activator 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition late endosomal/lysosomal adaptor, MAPK and MTOR activator 5

研究结论

Date Results Publications
2021-01-16 15:56:00 LAMTOR5 raises abnormal initiation of O-glycosylation in breast cancer metastasis via modulating GALNT1 activity. 31836847
2020-09-12 16:05:00 The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt-PCAF pathway in promotion of esophageal squamous cell carcinoma growth. 32313942
2020-03-28 11:34:00 biomarker of colorectal cancer which promotes invasion and migration via epithelial-mesenchymal transition 31987874
2020-02-15 13:04:00 Study found LAMTOR5 was overexpressed in human and Pten cKO mice head and neck squamous cell carcinoma (HNSCC), and its expression was significantly associated with patients' overall survival, lymph node metastasis and lymph node grade. Furthermore, LAMTOR5 expression was significantly correlated with the expression of immune checkpoints and macrophage markers. 31337951
2019-10-26 12:12:00 HBXIP elevated HOXB13 protein level in breast cancer cells. Mechanistically, HBXIP prevented chaperone-mediated autophagy (CMA)-dependent degradation of HOXB13 via enhancement of HOXB13 acetylation at the lysine 277 residue, causing the accumulation of HOXB13. 29471853

名称对应

Type IDs
Synonymous HBXIP, XIP
Gene
UniProtKB-ID: LTOR5_HUMAN, A0A0C4DGV4_HUMAN
UniprotKB: O43504, A0A0C4DGV4
UniParc: UPI0000138FFA, UPI0000205288
EMBL: CR542130, CR456866, AF029890, CH471122, AL390797, AY623819, BC062619
Ensembl: ENSG00000134248
KO: hsa:10542
Nucleutide sequences
EMBL-CDS: CAG46927.1, CAG33147.1, AAH62619.2, AAC52032.1, AAV30683.1, EAW56447.1
Gene_ORFName: hCG_40252
Ensembl_TRS: ENST00000602318, ENST00000614544, ENST00000256644
Protein sequencees
Ensembl_PRO: ENSP00000473439, ENSP00000256644, ENSP00000480529
RefSeq: NP_006393.2, NP_001369222.1
Others
UniRef100: UniRef100_O43504, UniRef100_A0A0C4DGV4
UniRef90: UniRef90_O43504, UniRef90_A0A0C4DGV4
UniRef50: UniRef50_Q9D1L9, UniRef50_O43504
UniGene: Hs.439815

全选

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