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10539 GLRX3

10539

GLRX3

glutaredoxin 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutaredoxin 3

研究结论

Date Results Publications
2021-04-17 13:38:00 GLRX3 Acts as a [2Fe-2S] Cluster Chaperone in the Cytosolic Iron-Sulfur Assembly Machinery Transferring [2Fe-2S] Clusters to NUBP1. 32429669
2020-11-21 13:12:00 Interactions of GMP with Human Glrx3 and with Saccharomyces cerevisiae Grx3 and Grx4 Converge in the Regulation of the Gcn2 Pathway. 32414791
2020-09-26 13:05:00 PICOT binding to chromatin-associated EED negatively regulates cyclin D2 expression by increasing H3K27me3 at the CCND2 gene promoter. 31527584
2020-08-22 15:31:00 PICOT (GLRX3) is a positive regulator of stress-induced DNA-damage response. 31176019
2019-11-02 12:08:00 PICOT knock-down in Jurkat T cells resulted in a reduced histone H3 lysine 27 trimethylation (H3K27me3) at the PRC2 target gene, myelin transcription factor 1 (MYT1), suggesting that PICOT binding to EED alters PRC2-regulated transcriptional repression, and potentially contributes to the epigenetic regulation of chromatin silencing and remodeling. 30595380

名称对应

Type IDs
Synonymous GLRX4, GRX3, GRX4, PICOT, TXNL2, TXNL3
Gene
UniProtKB-ID: GLRX3_HUMAN, A0A140VJK1_HUMAN
UniprotKB: O76003, A0A140VJK1
UniParc: UPI000006E4EA
EMBL: CH471066, AF118652, HM005388, BC005289, AK022131, AJ010841, BC014372, AF118649, AK021926, AL139123
Ensembl: ENSG00000108010
KO: hsa:10539
Nucleutide sequences
EMBL-CDS: CAA09375.1, EAW49152.1, AAH14372.2, AAF28844.1, EAW49154.1, BAG51067.1, BAG51059.1, EAW49155.1, AAH05289.1, AAF28841.1, AEE60988.1
Gene_ORFName: HUSSY-22
Ensembl_TRS: ENST00000368644, ENST00000331244, ENST00000481034
Protein sequencees
Ensembl_PRO: ENSP00000330836, ENSP00000435445, ENSP00000357633
RefSeq: XP_016870963.1, NP_001308909.1, NP_006532.2, NP_001186797.1
Others
UniRef100: UniRef100_O76003
UniRef90: UniRef90_O76003
UniRef50: UniRef50_O76003
UniGene: Hs.42644
CCDS: CCDS7661.1

全选

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