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10538 BATF

10538

BATF

basic leucine zipper ATF-like transcription factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition basic leucine zipper ATF-like transcription factor

研究结论

Date Results Publications
2020-05-23 10:59:00 results reveal that JunB, c-Jun, and Bach2 cooperate with BATF to contribute to the specificity of BATF-dependent cytokine induction in Th subsets. 31451674
2019-07-20 11:57:00 BATF-dependent pathogenic GM-CSF+ effector T cells are critical promoters of intestinal inflammation in graft-versus-host disease 29376889
2018-09-15 11:42:00 Findings demonstrate that peripheral and intrahepatic BATF expressions are dramatically increased in chronic hepatitis B (CHB) patients, which might boost the differentiation of Th17 cells and the release of associated cytokine during chronic HBV infection. 29164410
2018-01-20 10:42:00 BATF plays a key role in the differentiation of T helper cell subsets and Ig class-switching. Apart from that we suggest an important function in mast cell development and in murine models of allergic asthma, it was observed that mice deficient for Batf are protected from the disease. Hence, the previous findings on BATF make it an interesting target for the treatment of Th cell-derived-cytokine-driven diseases. 26970726
2018-01-06 11:26:00 Retinoic acid signaling and BATF productions are activated in IgAN patients compared with controls. 27073891

名称对应

Type IDs
Synonymous B-ATF, BATF1, SFA-2, SFA2
Gene
UniProtKB-ID: BATF_HUMAN
UniprotKB: Q16520
UniParc: UPI0000073D64
EMBL: D42106, AC007182, BC032294, AF016898, U15460
Ensembl: ENSG00000156127
KO: hsa:10538
Nucleutide sequences
EMBL-CDS: AAH32294.1, AAC78243.1, BAA07686.1, AAD51372.1, AAC50314.1
Ensembl_TRS: ENST00000286639
Protein sequencees
Ensembl_PRO: ENSP00000286639
RefSeq: NP_006390.1
Others
UniRef100: UniRef100_Q16520
UniRef90: UniRef90_O35284
UniRef50: UniRef50_O35284
UniGene: Hs.509964
CCDS: CCDS9843.1

全选

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研究热度

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