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1053 CEBPE

1053

CEBPE

CCAAT enhancer binding protein epsilon

protein-coding

Homo sapiens

基因描述

Type Description
Definition CCAAT enhancer binding protein epsilon

研究结论

Date Results Publications
2021-04-17 13:14:00 The CEBPE rs2239633 genetic polymorphism on susceptibility to childhood acute lymphoblastic leukemia: an updated meta-analysis. 33397280
2020-09-12 16:05:00 Loss of myeloid-specific lamin A/C drives lung metastasis through Gfi-1 and C/EBPepsilon-mediated granulocytic differentiation. 31912614
2020-07-18 12:16:00 A single amino acid deletion of either R247 (DeltaR) or S248 (DeltaS) was sufficient for the loss of C/EBP-epsilon transcriptional activity, while an amino acid substitution at S248 to alanine in C/EBP-epsilon (SA) had comparable transcriptional activity with the wild-type C/EBP-epsilon (WT). An acetylation mimic form of C/EBP-epsilon DeltaRS does not have transcriptional activity. C/EBP-epsilon DeltaRS interacts with... 31256937
2020-07-18 10:53:00 CEBPE expression was an independent prognostic factor for Acute Myeloid Leukemia survival, relapse and allogeneic transplantation, which will provide useful information for outcome prediction and therapeutic decisions. 31164135
2020-06-20 12:07:00 this study shows that gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy 31201888

名称对应

Type IDs
Synonymous C/EBP-epsilon, CRP1
Gene
UniProtKB-ID: CEBPE_HUMAN
UniprotKB: Q15744
UniParc: UPI000013C660
EMBL: U48865, BC035797, U80982, U48866
Ensembl: ENSG00000092067
KO: hsa:1053
Nucleutide sequences
EMBL-CDS: AAC50709.1, AAC51130.1, AAC50708.1, AAH35797.2
Ensembl_TRS: ENST00000206513
Protein sequencees
Ensembl_PRO: ENSP00000206513
RefSeq: NP_001796.2
Others
UniRef100: UniRef100_Q15744
UniRef90: UniRef90_Q15744
UniRef50: UniRef50_Q15744
UniGene: Hs.558308
CCDS: CCDS9589.1

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