| Type | Description |
|---|---|
| Definition | thioredoxin domain containing 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:28:00 | Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFbeta signaling through TGFBR1 stabilization. | 32848143 |
| 2019-09-14 10:42:00 | TXNDC5 mRNA and protein were highly upregulated in hypertrophied/failing mouse left ventricle. Targeted disruption of Txndc5 in mice revealed protective effects against isoproterenol-induced cardiac hypertrophy, reduced fibrosis by approximately 70%, and markedly improved left ventricle function. | 29535165 |
| 2013-07-06 11:24:00 | Hypoxia induced TXCNDC5 expression, which contributed to adiponectin expression, cytokine production and the cellular proliferation and migration of fibroblasts in rheumatoid arthritis. | 23326410 |
| 2013-05-25 11:04:00 | Txndc5 reflects the anti-steatotic properties of squalene and the sensitivity to lipid accumulation. | 22796066 |
| 2013-02-09 10:31:00 | ERp46 plays a protective role in palmitic acid -induced cell apoptosis by decreasing the endoplasmic reticulum stress response and might be a novel target for anti-diabetic drugs. | 22935416 |
| Type | IDs |
|---|---|
| Synonymous | AL022641, ERp46, PC-TRP |
| Gene |
UniProtKB-ID:
TXND5_MOUSE,
Q3TEE8_MOUSE,
A0A0R4J1Y7_MOUSE,
E9PXX7_MOUSE,
Q3UWX1_MOUSE
UniprotKB:
Q91W90,
Q3TEE8,
A0A0R4J1Y7,
E9PXX7,
Q3UWX1
UniParc:
UPI0000354800,
UPI00000E69AA,
UPI000000BACF,
UPI00005ABC3B
EMBL:
BC046789,
AK136046,
AY548112,
AY243534,
AK142049,
BC016252,
AK169680,
AC154747,
BC024505
Ensembl:
ENSMUSG00000038991
KO:
mmu:105245
|
| Nucleutide sequences |
EMBL-CDS:
AAS55652.1,
AAH24505.1,
AAH46789.3,
AAP68841.1,
AAH16252.2,
BAE24925.1,
BAE41300.1,
BAE22793.1
Ensembl_TRS:
ENSMUST00000035988,
ENSMUST00000162075,
ENSMUST00000160653
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041839,
ENSMUSP00000124516,
ENSMUSP00000124401
RefSeq:
NP_663342.3,
NP_001276527.1,
NP_001276528.1
|
| Others |
UniRef100:
UniRef100_Q91W90,
UniRef100_E9PXX7
UniRef90:
UniRef90_Q91W90
UniRef50:
UniRef50_Q8NBS9
UniGene:
Mm.28622
CCDS:
CCDS26463.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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