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10519 CIB1

10519

CIB1

calcium and integrin binding 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition calcium and integrin binding 1

研究结论

Date Results Publications
2021-03-13 13:18:00 Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components. 32917726
2021-01-23 12:57:00 Identification of calcium and integrin-binding protein 1 as a novel regulator of production of amyloid beta peptide using CRISPR/Cas9-based screening system. 32307772
2020-12-12 13:29:00 Gene expression is stable in a complete CIB1 knockout keratinocyte model. 32917957
2020-07-11 10:48:00 these results suggest that in resting platelets ASK1 is bound to CIB1 at low Ca2+ concentrations. Agonist-induced platelet activation causes an increase in intracellular Ca2+ concentration that leads to the dissociation of CIB1 from ASK1, allowing for proper dimerization through ASK1 N-terminal coiled-coil (NCC) domains. 31530712
2019-09-07 10:14:00 these findings suggest that the disruption of CIB1-EVER1-EVER2-dependent keratinocyte-intrinsic immunity underlies the selective susceptibility to beta-HPVs of epidermodysplasia verruciformis patients. 30068544

名称对应

Type IDs
Synonymous CIB, CIBP, KIP1, PRKDCIP, SIP2-28
Gene
UniProtKB-ID: CIB1_HUMAN, A0A140VK09_HUMAN
UniprotKB: Q99828, A0A140VK09
UniParc: UPI00001FEB83, UPI00001506F1
EMBL: AB021866, AB451406, CH471101, U82226, U83236, BC000846, AB451276, HM005549, CR456955, U85611, JQ246073
Ensembl: ENSG00000185043
KO: hsa:10519
Nucleutide sequences
EMBL-CDS: AAB39758.1, BAG70090.1, AEZ06077.1, CAG33236.1, AAB53387.1, EAX02090.1, BAA36281.1, BAG70220.1, AAC51106.1, AAH00846.1, AEE61146.1
Ensembl_TRS: ENST00000328649, ENST00000612800
Protein sequencees
Ensembl_PRO: ENSP00000479860, ENSP00000333873
RefSeq: XP_006720438.1, NP_006375.2, NP_001264693.1
Others
UniRef100: UniRef100_Q99828
UniRef90: UniRef90_Q99828
UniRef50: UniRef50_Q99828
UniGene: Hs.715556
CCDS: CCDS73781.1, CCDS10360.1

全选

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