| Type | Description |
|---|---|
| Definition | F-box and WD repeat domain containing 10 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:14:00 | FBXW10 promotes hepatocarcinogenesis in male patients and mice. | 31400758 |
| 2013-11-30 12:41:00 | O-GlcNAcylation is involved in the regulation of ubiquitination-related genes including FBXW10 | 23899520 |
| 2010-09-13 12:16:00 | Mislocalized lamins can induce ubiquitin-mediated proteasomal degradation of certain HP1 isoforms by activation of FBXW10, a member of the F-box family of proteins that is involved in E3 ubiquitin ligase activity. | 20498703 |
| Type | IDs |
|---|---|
| Synonymous | Fbw10, HREP, SM25H2, SM2SH2 |
| Gene |
UniProtKB-ID:
FBW10_HUMAN
UniprotKB:
Q5XX13
UniParc:
UPI000013E76E,
UPI0000200B33,
UPI000013EDB9,
UPI0000200B30
EMBL:
AY729024,
BC028364,
AC107982,
BI828401,
AL136822
Ensembl:
ENSG00000171931
KO:
hsa:10517
|
| Nucleutide sequences |
EMBL-CDS:
AAU43731.1,
CAB66756.1,
AAH28364.1
Ensembl_TRS:
ENST00000301938,
ENST00000308799,
ENST00000395665
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379025,
ENSP00000310382,
ENSP00000306937
RefSeq:
NP_001254515.1,
NP_001254514.1,
XP_011521928.1,
XP_011521927.1,
XP_016879509.1,
XP_016879510.1
|
| Others |
UniRef100:
UniRef100_Q5XX13
UniRef90:
UniRef90_Q5XX13
UniRef50:
UniRef50_Q5XX13
UniGene:
Hs.592128
CCDS:
CCDS11199.3,
CCDS58524.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31400758 |
FBXW10 promotes hepatocarcinogenesis in male patients and mice. Carcinogenesis Yuan-Deng Luo , Jie Zhang , Lei Fang , Yan-Yin Zhu , Yue-Mei You , Cheng-Cheng Zhang , Ping Zheng , Lei-Da Zhang , Liang-Yu Yin , Feng Xia , Ping Bie , Chuan-Ming Xie |
2020-07-10 | - |
| 26673895 |
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray Kırlı , Samir Karaca , Heinz Jürgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk Görlich |
2015-01-01 |
CHA1,
KRR1,
SRO9,
STE50,
RRP7,
RNQ1,
DCC1,
GBP2,
SAT4,
RVS161,
YCR016W,
PWP2,
SSK22,
SOL2,
PAT1,
YCR087C-A,
OCA4,
MOB2,
EPL1,
BUD27,
FRS2,
LOC1,
YFR016C,
LSB3,
RPL2A,
PHO4,
SAP155,
IRC6,
ENT4,
PRP19,
RIX7,
YLL032C,
FRA1,
ISA1,
SPA2,
PUF3,
RPL8B,
NOC3,
SSL1,
SSK1,
NSE1,
RLP24,
SDO1,
ADE16,
RPL15A,
STU2,
RPS0B,
FRS1,
BMT6,
KIN2,
HRT3,
REX3,
YLR108C,
CFT2,
MSL5,
ACE2,
STM1,
YLR157C-A,
APS1,
CBF5,
SWI6,
SKG3,
HCR1,
PWP1,
NOP56,
BUR2,
GPN3,
DBP9,
GCD7,
SGD1,
STE11,
NMD4,
RPS22B,
ROM2,
STP3,
IKI3,
REH1,
AFG2,
UTP21,
ATG17,
TUS1,
MAG2,
ATG23,
RPS1A,
FPR4,
PDP3,
CDC24,
RBG1,
FUN12,
MTW1,
PRP45,
MAK16,
ECM1,
GPB2,
VPS8,
KIN3,
CDC15,
YAT1,
WHI4
|
| 23899520 |
FBXW10 is negatively regulated in transcription and expression level by protein O-GlcNAcylation. Biochem. Biophys. Res. Commun. Zhou Feng , Yan Hui , Li Ling , Liu Xiaoyan , Wang Yuqiu , Wang Peng , Zhang Lianwen |
2013-08-23 |
FBXW10
|
| 21145461 |
Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. Cell Eric J Bennett , John Rush , Steven P Gygi , J Wade Harper |
2010-12-10 | - |
| 20498703 |
PLoS One Pankaj Chaturvedi , Veena K Parnaik |
2010-05-13 | - |
| 19028597 |
Int J Biochem Cell Biol Frédéric Ebstein , Nicole Lange , Sabrina Urban , Ulrike Seifert , Elke Krüger , Peter-Michael Kloetzel |
2009-05-01 | - |
| 16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
| 15520277 |
Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev. Jianping Jin , Timothy Cardozo , Ruth C Lovering , Stephen J Elledge , Michele Pagano , J Wade Harper |
2004-11-01 |
Fbxl14,
Fbxw11,
Fbxo4,
Fbxo38,
Fbxw17,
Fbxo40,
Fbxw13,
Fbxl21,
Fbxo42,
Fbxw10,
Fbxl16,
Fbxo11,
Kdm2a,
Fbxo44,
Fbxo21,
Fbxw8,
Fbxl18,
Fbxo27,
Fbxl19,
Fbxw19,
Fbxl5,
Fbxo46,
Fbxo45,
Fbxl4,
Fbxo10,
Skp2,
Fbxw2,
Fbxw4,
Fbxw5,
Fbxl6,
Kdm2b,
Fbxl12,
Fbxw16,
Fbxl13,
Fbxo41,
Lmo7,
Fbxw15,
Fbxw20,
Fbxl7,
Fbxw7,
Fbxw14,
Fbxl17,
Fbxo16,
Fbxo17,
Fbxo15,
Fbxl8,
Fbxl3,
Fbxw18,
Fbxo3,
Fbxo39,
Fbxo36,
Fbxo25,
Fbxo32,
Fbxo28,
Fbxl15,
Fbxw9,
Fbxo24,
Fbxo30,
Fbxo22,
Fbxl2,
Fbxl20,
Fbxl22,
Fbxo43,
Fbxo34,
Fbxo17,
Myc,
Fbxl4,
jet,
Fbw5,
Rca1,
CycE,
CG9003,
CG6758,
Ppa,
ago,
CG4911,
pall,
CG32085,
CG11658,
Skp2,
Kdm2,
FBXO11,
CG5961,
Fbxl7,
slmb,
CG2010,
FBXW10,
FBXO27,
FBXO36,
FBXL14,
FBXL16,
FBXO41,
FBXO39,
FBXO45,
FBXO15,
FBXL13,
FBXO28,
FBXO46,
FBXO33
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 11230166 |
Genome Res. S Wiemann , B Weil , R Wellenreuther , J Gassenhuber , S Glassl , W Ansorge , M Böcher , H Blöcker , S Bauersachs , H Blum , J Lauber , A Düsterhöft , A Beyer , K Köhrer , N Strack , H W Mewes , B Ottenwälder , B Obermaier , J Tampe , D Heubner , R Wambutt , B Korn , M Klein , A Poustka |
2001-03-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员