| Type | Description |
|---|---|
| Definition | pelota mRNA surveillance and ribosome rescue factor |
| Date | Results | Publications |
|---|---|---|
| 2017-07-22 13:36:00 | increased activity of the PI3K/AKT signaling pathway in Pelo-deficient skin might conflict with the dephosphorylation of profilaggrin and thereby affect its proper processing into filaggrin monomers and ultimately the epidermal differentiation | 27164299 |
| 2016-01-23 11:13:00 | These results suggest that PELO negatively regulates the PI3K/AKT pathway and that the enhanced activity of PI3K/AKT and subsequent FOXO1 inhibition are responsible for the impaired development of spermatogonial stem cells in mutant testes. | 25661254 |
| 2015-04-25 12:55:00 | Results indicate that PELO plays an important role in the establishment of pluripotency and differentiation of ESCs into ExEn lineage through activation of BMP signaling. | 24835669 |
| 2014-08-09 11:14:00 | these results not only define GTPBP2 as a ribosome rescue factor but also unmask the disease potential of mutations in nuclear-encoded tRNA genes. | 25061210 |
| 2010-01-21 00:00:00 | cDNA cloning, genomic structure, and chromosomal localization | 12438745 |
| Type | IDs |
|---|---|
| Synonymous | AA409897, AI852218 |
| Gene |
UniProtKB-ID:
PELO_MOUSE
UniprotKB:
Q80X73
UniParc:
UPI000024E0A1
EMBL:
AF148639,
AK170635,
AF148638,
BC050209,
BC057160
Ensembl:
ENSMUSG00000042275
KO:
mmu:105083
|
| Nucleutide sequences |
EMBL-CDS:
BAE41926.1,
AAH50209.1,
AAH57160.1,
AAK58117.1,
AAK58116.1
Ensembl_TRS:
ENSMUST00000109226
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104849
RefSeq:
NP_598819.2
|
| Others |
UniRef100:
UniRef100_Q80X73
UniRef90:
UniRef90_Q9BRX2
UniRef50:
UniRef50_Q9BRX2
UniGene:
Mm.486295
CCDS:
CCDS26788.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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