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10494 STK25

10494

STK25

serine/threonine kinase 25

protein-coding

Homo sapiens

基因描述

Type Description
Definition serine/threonine kinase 25

研究结论

Date Results Publications
2021-04-03 13:31:00 STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism. 32292165
2019-05-11 10:18:00 Our results demonstrated that STK25 negatively regulates the proliferation and glycolysis via GOLPH3-dependent mTOR signaling. Accordingly, STK25 could be a potential therapeutic target for the treatment of CRC. 29996891
2019-05-04 11:53:00 Loss of STK25 promotes YAP/TAZ activation and enhanced cellular proliferation, even under normally growth-suppressive conditions both in vitro and in vivo. 30948712
2019-04-27 12:15:00 hYSK1 blocks the p21(WAF1/Cip1) functions by direct interaction and inhibits the p16(INK4a) expression and induces MMP-2 expression by its regulations of SP-1 transcriptional activity under the hypoxia conditions. 30646538
2016-10-22 11:56:00 STK25 regulates lipid partitioning in human liver cells by controlling TAG synthesis as well as lipolytic activity and thereby NEFA release from lipid droplets for beta-oxidation and TAG secretion. 26553096

名称对应

Type IDs
Synonymous SOK1, YSK1
Gene
UniProtKB-ID: STK25_HUMAN, B3KRS6_HUMAN, B4DVS7_HUMAN, B4DMA5_HUMAN, A0A0S2Z4Y2_HUMAN, A0A024R4B2_HUMAN, B4E185_HUMAN, Q96BA2_HUMAN
UniprotKB: O00506, B3KRS6, B4DVS7, B4DMA5, A0A0S2Z4Y2, A0A024R4B2, B4E185, Q96BA2
UniParc: UPI000006F6A5, UPI0001915479, UPI00017A8833, UPI00017A760A, UPI00003723EF, UPI000013FE30, UPI00017A7D62, UPI0000000C8C
EMBL: CH471063, AK092161, DQ093965, AK303719, AK291808, BC007852, BC091505, AC110299, AK301214, D63780, X99325, BT019961, KU178530, KU178528, BC015793, AK291947, AK297374, AK315966
Ensembl: ENSG00000115694
KO: hsa:10494
Nucleutide sequences
EMBL-CDS: EAW71265.1, BAA20420.1, BAH14337.1, BAF84497.1, AAV38764.1, CAA67700.1, AAH07852.1, BAF84636.1, AAY88740.1, AAY14683.1, AAH91505.1, BAG52488.1, BAG62789.1, BAG59817.1, ALQ33988.1, ALQ33986.1, EAW71266.1, BAG64697.1, AAH15793.1
Gene_ORFName: hCG_33046
Ensembl_TRS: ENST00000405883, ENST00000316586, ENST00000403346, ENST00000401869, ENST00000543554, ENST00000405585, ENST00000535007
Protein sequencees
Ensembl_PRO: ENSP00000384162, ENSP00000384444, ENSP00000385541, ENSP00000444886, ENSP00000325748, ENSP00000446008, ENSP00000385687
RefSeq: NP_001269236.1, XP_016858659.1, NP_001269237.1, NP_001258906.1, NP_006365.2, NP_001269234.1, XP_011508795.1, XP_011508796.1, NP_001258908.1, NP_001258909.1, NP_001258907.1, XP_011508798.1, XP_016858658.1, XP_016858657.1, XP_016858660.1, NP_001269235.1, XP_011508797.1
Others
UniRef100: UniRef100_B4DMA5, UniRef100_B4E185, UniRef100_Q96BA2, UniRef100_A0A2J8IV19, UniRef100_O00506, UniRef100_B4DVS7, UniRef100_B3KRS6
UniRef90: UniRef90_O00506, UniRef90_A0A2K6G7U2, UniRef90_B4DMA5, UniRef90_A0A2I2YTA4
UniRef50: UniRef50_A0A2I3LJ65, UniRef50_G3WKP7, UniRef50_O00506, UniRef50_F1PTW5
UniGene: Hs.516807
CCDS: CCDS2549.1, CCDS63200.1, CCDS63199.1

全选

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