Type | Description |
---|---|
Definition | serine/threonine kinase 25 |
Date | Results | Publications |
---|---|---|
2021-04-03 13:31:00 | STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism. | 32292165 |
2019-05-11 10:18:00 | Our results demonstrated that STK25 negatively regulates the proliferation and glycolysis via GOLPH3-dependent mTOR signaling. Accordingly, STK25 could be a potential therapeutic target for the treatment of CRC. | 29996891 |
2019-05-04 11:53:00 | Loss of STK25 promotes YAP/TAZ activation and enhanced cellular proliferation, even under normally growth-suppressive conditions both in vitro and in vivo. | 30948712 |
2019-04-27 12:15:00 | hYSK1 blocks the p21(WAF1/Cip1) functions by direct interaction and inhibits the p16(INK4a) expression and induces MMP-2 expression by its regulations of SP-1 transcriptional activity under the hypoxia conditions. | 30646538 |
2016-10-22 11:56:00 | STK25 regulates lipid partitioning in human liver cells by controlling TAG synthesis as well as lipolytic activity and thereby NEFA release from lipid droplets for beta-oxidation and TAG secretion. | 26553096 |
Type | IDs |
---|---|
Synonymous | SOK1, YSK1 |
Gene |
UniProtKB-ID:
STK25_HUMAN,
B3KRS6_HUMAN,
B4DVS7_HUMAN,
B4DMA5_HUMAN,
A0A0S2Z4Y2_HUMAN,
A0A024R4B2_HUMAN,
B4E185_HUMAN,
Q96BA2_HUMAN
UniprotKB:
O00506,
B3KRS6,
B4DVS7,
B4DMA5,
A0A0S2Z4Y2,
A0A024R4B2,
B4E185,
Q96BA2
UniParc:
UPI000006F6A5,
UPI0001915479,
UPI00017A8833,
UPI00017A760A,
UPI00003723EF,
UPI000013FE30,
UPI00017A7D62,
UPI0000000C8C
EMBL:
CH471063,
AK092161,
DQ093965,
AK303719,
AK291808,
BC007852,
BC091505,
AC110299,
AK301214,
D63780,
X99325,
BT019961,
KU178530,
KU178528,
BC015793,
AK291947,
AK297374,
AK315966
Ensembl:
ENSG00000115694
KO:
hsa:10494
|
Nucleutide sequences |
EMBL-CDS:
EAW71265.1,
BAA20420.1,
BAH14337.1,
BAF84497.1,
AAV38764.1,
CAA67700.1,
AAH07852.1,
BAF84636.1,
AAY88740.1,
AAY14683.1,
AAH91505.1,
BAG52488.1,
BAG62789.1,
BAG59817.1,
ALQ33988.1,
ALQ33986.1,
EAW71266.1,
BAG64697.1,
AAH15793.1
Gene_ORFName:
hCG_33046
Ensembl_TRS:
ENST00000405883,
ENST00000316586,
ENST00000403346,
ENST00000401869,
ENST00000543554,
ENST00000405585,
ENST00000535007
|
Protein sequencees |
Ensembl_PRO:
ENSP00000384162,
ENSP00000384444,
ENSP00000385541,
ENSP00000444886,
ENSP00000325748,
ENSP00000446008,
ENSP00000385687
RefSeq:
NP_001269236.1,
XP_016858659.1,
NP_001269237.1,
NP_001258906.1,
NP_006365.2,
NP_001269234.1,
XP_011508795.1,
XP_011508796.1,
NP_001258908.1,
NP_001258909.1,
NP_001258907.1,
XP_011508798.1,
XP_016858658.1,
XP_016858657.1,
XP_016858660.1,
NP_001269235.1,
XP_011508797.1
|
Others |
UniRef100:
UniRef100_B4DMA5,
UniRef100_B4E185,
UniRef100_Q96BA2,
UniRef100_A0A2J8IV19,
UniRef100_O00506,
UniRef100_B4DVS7,
UniRef100_B3KRS6
UniRef90:
UniRef90_O00506,
UniRef90_A0A2K6G7U2,
UniRef90_B4DMA5,
UniRef90_A0A2I2YTA4
UniRef50:
UniRef50_A0A2I3LJ65,
UniRef50_G3WKP7,
UniRef50_O00506,
UniRef50_F1PTW5
UniGene:
Hs.516807
CCDS:
CCDS2549.1,
CCDS63200.1,
CCDS63199.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员