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10492 SYNCRIP

10492

SYNCRIP

synaptotagmin binding cytoplasmic RNA interacting protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition synaptotagmin binding cytoplasmic RNA interacting protein

研究结论

Date Results Publications
2020-09-05 13:53:00 ATP binds nucleic-acid-binding domains beyond RRM fold. 31791586
2020-06-20 12:32:00 the terminal loop of pri-let-7a was shown to be the main contributor for its interaction with SYNCRIP. Functional studies demonstrated that the SYNCRIP RRM2-3 domain can promote the processing of pri-let-7a 31907208
2020-04-04 12:43:00 Identification of the frequent presence of hnRNP R and hnRNP Q in frontotemporal lobar degeneration (FTLD)-FUS inclusions suggests a potential role for these hnRNPs in FTLD-FUS pathogenesis and supports the role of dysfunctional RNA metabolism in FTLD. 30755280
2019-12-28 12:18:00 Results indentified two candidate haploinsufficient genes contiguous at 6q14 SYNCRIP (encoding hnRNP-Q) and SNHG5 (that hosts snoRNAs), both involved in regulating RNA maturation and translation inT-cell acute lymphoblastic leukemia (T-ALL). 30266814
2019-03-30 10:56:00 The EGF/hnRNP Q1-induced translation of Aurora-A mRNA is mediated by the mTOR and ERK pathways. 29884818

名称对应

Type IDs
Synonymous GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q
Gene
UniProtKB-ID: HNRPQ_HUMAN, B7Z645_HUMAN, Q59GL1_HUMAN
UniprotKB: O60506, B7Z645, Q59GL1
UniParc: UPI000006E835, UPI00004F6B82, UPI00004236B4, UPI0000247061, UPI0000EE1E81, UPI000013CF84, UPI0000470B17
EMBL: AK222776, AF155568, BC032643, AK299796, AL136082, BC015575, CH471051, AB209098, AY034483, AY034482, AY034481, AF037448, BC040844
Ensembl: ENSG00000135316
KO: hsa:10492
Nucleutide sequences
EMBL-CDS: AAH32643.1, EAW48629.1, EAW48626.1, AAH15575.1, AAC12926.1, AAK59705.1, AAK59703.1, AAD38198.1, BAD96496.1, EAW48625.1, AAK59704.1, EAW48630.1, AAH40844.1, BAH13131.1, EAW48623.1, BAD92335.1
Gene_ORFName: hCG_401112
Ensembl_TRS: ENST00000355238, ENST00000369622, ENST00000616122
Protein sequencees
Ensembl_PRO: ENSP00000358635, ENSP00000347380, ENSP00000484577
RefSeq: XP_016865667.1, XP_016865666.1, NP_001153146.1, NP_001153148.1, XP_016865665.1, NP_001153149.1, NP_001153145.1, XP_005248693.1, NP_006363.4, XP_005248694.1, NP_001153147.1, XP_016865668.1, XP_016865669.1, XP_005248692.1, NP_001240700.1
Others
UniRef100: UniRef100_O60506, UniRef100_B7Z645, UniRef100_Q59GL1
UniRef90: UniRef90_B7Z645, UniRef90_O60506
UniRef50: UniRef50_O60506
UniGene: Hs.571177
CCDS: CCDS5005.1, CCDS55041.1

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