| Type | Description |
|---|---|
| Definition | Sec23 homolog A, coat complex II component |
| Date | Results | Publications |
|---|---|---|
| 2020-01-04 10:11:00 | Transduction with BBF2H7/CREB3L2 upregulates SEC23A protein in erythroblasts and partially corrects the hypo-glycosylation phenotype associated with CDAII. | 29536501 |
| 2019-03-16 10:05:00 | identified Sec23a, a gene target of miR-200c, suppresses miR-200c augmented oligometastatic to polymetastatic progression via its secretome. Firstly, miR-200c over-expression and Sec23a interference accelerated oligometastatic to polymetatic progression. Secondly, Sec23a functions downstream of miR-200c. | 30301603 |
| 2018-12-22 10:28:00 | This larger GWAS yields two loci harboring genome-wide significant variants affecting serum 25-hydroxyvitamin D levels (P = 4.7x10(-9) at rs8018720 in SEC23A, and P = 1.9x10(-14) at rs10745742 in AMDHD1). | 29343764 |
| 2018-10-06 12:17:00 | these data demonstrate an equivalent function for SEC23A/B, with evolutionary shifts in the transcription program likely accounting for the distinct phenotypes of SEC23A/B deficiency within and across species, a paradigm potentially applicable to other sets of paralogous genes. | 30065114 |
| 2018-05-12 10:33:00 | Mutation on serine207 of Sec23A protein changes Unc-51 like kinase 1(ULK 1) targeted phosphorylation. During elevated autophagy, induced by amino acid starvation, rapamycin, or overexpression of ULK1,phosphorylation of Sec23A reduced the interaction between vesicular transport proteins Sec23A and Sec31A. | 28486929 |
| Type | IDs |
|---|---|
| Synonymous | CLSD, hSec23A |
| Gene |
UniProtKB-ID:
SC23A_HUMAN
UniprotKB:
Q15436
UniParc:
UPI0000229749,
UPI000013EC46
EMBL:
AK127355,
X97064,
AL109628,
BC036649,
AK312259
Ensembl:
ENSG00000100934
KO:
hsa:10484
|
| Nucleutide sequences |
EMBL-CDS:
AAH36649.1,
BAG35191.1,
CAA65774.1,
BAG54494.1
Ensembl_TRS:
ENST00000537403,
ENST00000307712
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000306881,
ENSP00000444193
RefSeq:
NP_006355.2,
XP_016876417.1,
XP_011534657.1,
XP_005267319.1
|
| Others |
UniRef100:
UniRef100_Q15436
UniRef90:
UniRef90_Q15436
UniRef50:
UniRef50_Q15436
UniGene:
Hs.272927
CCDS:
CCDS9668.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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