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10482 NXF1

10482

NXF1

nuclear RNA export factor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition nuclear RNA export factor 1

研究结论

Date Results Publications
2021-03-13 13:17:00 The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression. 31940815
2020-01-25 10:11:00 Using iCLIP, we show that the export receptor Nxf1 and two TREX subunits, Alyref and Chtop, are recruited to the whole mRNA co-transcriptionally via splicing but before 3' end processing. 31104896
2019-07-20 12:17:00 NXF1 is involved in coordinating transcriptional dynamics, 3' end processing, and nuclear export of long transcripts, implicating NXF1 as a nexus of gene regulation. 30819645
2018-12-22 12:23:00 Gain or loss-of-function experiments revealed NXF1 selectively regulates TLR7-driven IRF5 transcriptional activity, suggesting a new role for NXF1 in the IRF5 signaling pathway. 28578407
2018-12-22 10:28:00 repeat RNA-sequestration of SRSF1 triggers the NXF1-dependent nuclear export of C9ORF72 transcripts retaining expanded hexanucleotide repeats 28677678

名称对应

Type IDs
Synonymous MEX67, TAP
Gene
UniProtKB-ID: NXF1_HUMAN, Q59E96_HUMAN
UniprotKB: Q9UBU9, Q59E96
UniParc: UPI00004F6EA7, UPI0000577975, UPI00000012B9
EMBL: AK027192, AF126246, BC004904, AB209915, AF112880, U80073, AP001160, AK304137, AJ132712, BC028041, CH471076
Ensembl: ENSG00000162231
KO: hsa:10482
Nucleutide sequences
EMBL-CDS: BAG65031.1, AAD20016.1, AAB81111.1, CAA10753.1, AAD39102.1, AAH04904.1, EAW74105.1, AAH28041.1, BAD93152.1
Ensembl_TRS: ENST00000532297, ENST00000294172, ENST00000531709
Protein sequencees
Ensembl_PRO: ENSP00000453885, ENSP00000294172, ENSP00000436679
RefSeq: NP_006353.2, NP_001074960.1
Others
UniRef100: UniRef100_Q9UBU9, UniRef100_Q59E96
UniRef90: UniRef90_A0A667IHS4, UniRef90_Q9UBU9
UniRef50: UniRef50_A0A6I8SYL7, UniRef50_Q9UBU9
UniGene: Hs.523739, Hs.601546
CCDS: CCDS44629.1, CCDS8037.1

全选

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