例如:"NBL1", "4681", "drought"
收藏
10477 UBE2E3

10477

UBE2E3

ubiquitin conjugating enzyme E2 E3

protein-coding

Homo sapiens

基因描述

Type Description
Definition ubiquitin conjugating enzyme E2 E3

研究结论

Date Results Publications
2018-10-27 11:21:00 Cells depleted of UBE2E3 become senescent in the absence of overt DNA damage and have a distinct senescence-associated secretory phenotype, increased mitochondrial and lysosomal mass, an increased sensitivity to mitochondrial and lysosomal poisons, and an increased basal autophagic flux. 29879550
2015-10-03 10:17:00 Data indicate that ubiquitin-conjugating enzyme UBE2E3 and importin 11 (Imp-11)promote the nuclear accumulation and activity of transcription factor NF-E2 (Nrf2) by restricting the transcription factor from partitioning to the mitochondria. 25378586
2010-06-30 22:05:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614
2010-01-21 00:00:00 UBE2E3 is essential for the proliferation of RPE-1 cells and is downregulated during RPE layer maturation in the developing mouse eye. 18614808

名称对应

Type IDs
Synonymous UBCH9, UbcM2
Gene
UniProtKB-ID: UB2E3_HUMAN, R4GNG6_HUMAN
UniprotKB: Q969T4, R4GNG6
UniParc: UPI00000040F8, UPI00006C05F5
EMBL: AK314145, BC003554, AB017644, BT019345, AF085362, BC092407, AC068196, AC104076, CH471058, AF136176
Ensembl: ENSG00000170035
KO: hsa:10477
Nucleutide sequences
EMBL-CDS: EAX10990.1, AAY14882.1, AAV38152.1, AAH92407.1, BAG36833.1, AAP97266.1, BAA76544.1, AAD40197.1, EAX10989.1, AAH03554.1
Ensembl_TRS: ENST00000410062, ENST00000602710, ENST00000602959, ENST00000392415, ENST00000602632
Protein sequencees
Ensembl_PRO: ENSP00000473639, ENSP00000386788, ENSP00000473623, ENSP00000376215, ENSP00000473642
RefSeq: XP_011508794.1, NP_006348.1, NP_872619.1, NP_001265484.1, XP_016858655.1, XP_016858656.1, NP_001265483.1, XP_005246301.1
Others
UniRef100: UniRef100_R4GNG6, UniRef100_Q969T4
UniRef90: UniRef90_R4GNG6, UniRef90_Q969T4
UniRef50: UniRef50_Q969T4, UniRef50_R4GNG6
UniGene: Hs.470804
CCDS: CCDS2282.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员