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10474 TADA3

10474

TADA3

transcriptional adaptor 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition transcriptional adaptor 3

研究结论

Date Results Publications
2020-01-11 10:50:00 ADA3 expression level elevates in non-small cell lung cancer and correlates with poor overall survival in non-small cell lung cancer patients 30954347
2019-11-09 11:57:00 a pro-apoptotic mechanism centered on the intrinsic (mitochondrial) pathway and regulated by PCAF/ADA3 can influence the progression from premalignant to malignant change, and thus act as a tumor suppression mechanism in gastric cancer. 29670108
2018-05-05 10:16:00 These results reveal a novel RTK-AKT-p300-ADA3 signaling pathway involved in growth factor-induced cell cycle progression. 28759294
2018-03-31 12:06:00 PCAF and ADA3 transcriptionally regulate PACS1 and PACS1 is a key regulator of BAX/BAK oligomerization and the intrinsic (mitochondrial) pathway to apoptosis. 28060382
2017-08-12 11:18:00 ADA3 overexpression enhances cell proliferation that is associated with increased expression of c-MYC. Expression patterns with respect to ADA3/c-MYC can divide patients into four significantly different subgroups, with c-MYC High and ADA3 Low status independently predicting poor survival in patients. 27852327

名称对应

Type IDs
Synonymous ADA3, NGG1, STAF54, TADA3L, hADA3
Gene
UniProtKB-ID: TADA3_HUMAN, A8K899_HUMAN, A0A024R2D7_HUMAN
UniprotKB: O75528, A8K899, A0A024R2D7
UniParc: UPI000013EFDE, UPI00015DA96E, UPI000006F454
EMBL: CH471055, AF069733, BC013433, GQ900925, AK292264, AK000228, BC009240, CR533543, AL117487
Ensembl: ENSG00000171148
KO: hsa:10474
Nucleutide sequences
EMBL-CDS: EAW63994.1, CAB55957.1, AAH13433.1, AAH09240.1, AAC39903.1, CAG38574.1, BAF84953.1, ADO22442.1, EAW63997.1
Gene_ORFName: hCG_21549
Ensembl_TRS: ENST00000440161, ENST00000301964, ENST00000343450
Protein sequencees
Ensembl_PRO: ENSP00000343649, ENSP00000393471, ENSP00000307684
RefSeq: NP_006345.1, NP_597814.1, NP_001265199.1
Others
UniRef100: UniRef100_O75528, UniRef100_A8K899
UniRef90: UniRef90_Q8R0L9, UniRef90_O75528
UniRef50: UniRef50_Q8R0L9, UniRef50_O75528
UniGene: Hs.386390
CCDS: CCDS2583.1, CCDS2584.1

全选

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