| Type | Description |
|---|---|
| Definition | progesterone immunomodulatory binding factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:54:00 | PIBF1 suppresses the ATR/CHK1 signaling pathway and promotes proliferation and motility of triple-negative breast cancer cells. | 32529408 |
| 2020-11-28 13:11:00 | Characterisation of serum progesterone and progesterone-induced blocking factor (PIBF) levels across trimesters in healthy pregnant women. | 32123187 |
| 2019-11-23 12:12:00 | In conditioned media of PIBF-deficient JEG-3 cells, primary lung and ovarian cancer cells MMP9 activity was reduced. PIBF silencing resulted in increased E-cadherin expression, suggesting that by down regulating E-cadherin expression, PIBF might interfere with the cell-cell adhesion mechanisms and by increasing MMP activity induced extracellular matrix degradation, facilitates the invasion of tumor cells. | 29107859 |
| 2018-12-22 10:10:00 | We found at high levels of expression of PIBF protein in epithelial ovarian cancer patients. These data demonstrate that tumor cells can secrete PIBF to escape the immune system | 29962287 |
| 2017-12-09 10:53:00 | blood and placental tissue level expression of PIBF is concordant and correlates with both progesterone receptor expression status as well as final pregnancy outcome | 27728856 |
| Type | IDs |
|---|---|
| Synonymous | C13orf24, CEP90, JBTS33, PIBF |
| Gene |
UniProtKB-ID:
PIBF1_HUMAN
UniprotKB:
Q8WXW3
UniParc:
UPI00001418B9,
UPI00001C05E0,
UPI0006CE6137,
UPI00001C1500
EMBL:
AY370776,
BC051911,
AF330046,
Y09631,
AY375528,
AL354720,
AL391384
Ensembl:
ENSG00000083535
KO:
hsa:10464
|
| Nucleutide sequences |
EMBL-CDS:
AAQ67659.1,
AAH51911.1,
AAL37481.1,
CAA70844.1,
AAQ73282.1
Ensembl_TRS:
ENST00000615625,
ENST00000326291
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000483286,
ENSP00000317144
RefSeq:
XP_016875843.1,
XP_016875840.1,
XP_011533188.1,
XP_011533187.1,
XP_016875841.1,
NP_001336584.1,
XP_011533184.1,
XP_024305082.1,
XP_016875839.1,
NP_006337.2,
XP_011533186.1
|
| Others |
UniRef100:
UniRef100_Q8WXW3
UniRef90:
UniRef90_Q8WXW3
UniRef50:
UniRef50_Q8WXW3
UniGene:
Hs.441926
CCDS:
CCDS31991.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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