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10450 PPIE

10450

PPIE

peptidylprolyl isomerase E

protein-coding

Homo sapiens

基因描述

Type Description
Definition peptidylprolyl isomerase E

研究结论

Date Results Publications
2019-11-23 10:07:00 Study of datasets analyzing the gene expression profiles and DNA methylation data of gestational Diabetes Mellitus (GDM) and confirmed through real time PCR in placenta tissue of three GDM samples and three normal samples identified Oas1, Ppie, Polr2g as possible pathogenic target genes of GDM by combining protein-protein interaction analysis. 30389953
2012-01-14 11:58:00 CypE is a host restriction factor that inhibits the functions of nucleoprotein, as well as viral replication and transcription, by impairing the formation of the viral ribonucleoprotein complex. 21887220
2010-09-15 22:05:00 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) 20532202
2010-09-13 11:46:00 binding of H3K4me3 to PHD3 domain of MLL and binding of the CYP33 RRM domain to PHD3 are mutually inhibitory, implying that PHD3 is a molecular switch for the transition between activation and repression of target genes 20677832
2010-07-19 11:28:00 PPIase domain of CyP33 regulates the conformation of MLL1 through proline isomerization within the PHD3-Bromo linker, thereby disrupting the PHD3-Bromo interface and facilitating binding of the MLL1-PHD3 domain to the CyP33-RRM domain. 20541251

名称对应

Type IDs
Synonymous CYP-33, CYP33
Gene
UniProtKB-ID: PPIE_HUMAN, B3KSZ1_HUMAN
UniprotKB: Q9UNP9, B3KSZ1
UniParc: UPI0000128C84, UPI00002057ED, UPI000002A7A4, UPI0000E1E80F
EMBL: BC107736, AF104012, AF042385, CH471059, AF104013, AK094660, AL033527, AL049824, AF042386, DQ160195, BC008451, AL035404, BC004898, AK313666
Ensembl: ENSG00000084072
KO: hsa:10450
Nucleutide sequences
EMBL-CDS: BAG36418.1, AAI07737.1, AAC00006.1, AAD19906.1, AAZ93379.1, AAH04898.1, AAC00007.1, AAH08451.1, EAX07255.1, AAD19907.1, BAG52903.1
Ensembl_TRS: ENST00000324379, ENST00000372830, ENST00000356511
Protein sequencees
Ensembl_PRO: ENSP00000348904, ENSP00000361918, ENSP00000312769
RefSeq: XP_024306020.1, XP_024306045.1, XP_024306032.1, NP_001306222.1, NP_001181936.1, XP_016855541.1, NP_982281.1, XP_006710353.1, XP_016855540.1, NP_006103.1, XP_006710352.1, XP_011538803.1
Others
UniRef100: UniRef100_Q9UNP9
UniRef90: UniRef90_Q9UNP9
UniRef50: UniRef50_Q9UNP9
UniGene: Hs.524690
CCDS: CCDS443.1, CCDS53299.1, CCDS442.1

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