Architecture of the human interactome defines protein communities and disease networks.

Nature     Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper

Unfavorable neuroblastoma prognostic factor NLRR2 inhibits cell differentiation by transcriptional induction through JNK pathway.

Cancer Sci.     Afzal Sheikh , Atsushi Takatori , Md Shamim Hossain , Md Kamrul Hasan , Masatoshi Tagawa , Hiroki Nagase , Akira Nakagawara

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.

Proc. Natl. Acad. Sci. U.S.A.     Cornelius A Rietveld , Tõnu Esko , Gail Davies , Tune H Pers , Patrick Turley , Beben Benyamin , Christopher F Chabris , Valur Emilsson , Andrew D Johnson , James J Lee , Christiaan de Leeuw , Riccardo E Marioni , Sarah E Medland , Michael B Miller , Olga Rostapshova , Sven J van der Lee , Anna A E Vinkhuyzen , Najaf Amin , Dalton Conley , Jaime Derringer , Cornelia M van Duijn , Rudolf Fehrmann , Lude Franke , Edward L Glaeser , Narelle K Hansell , Caroline Hayward , William G Iacono , Carla Ibrahim-Verbaas , Vincent Jaddoe , Juha Karjalainen , David Laibson , Paul Lichtenstein , David C Liewald , Patrik K E Magnusson , Nicholas G Martin , Matt McGue , George McMahon , Nancy L Pedersen , Steven Pinker , David J Porteous , Danielle Posthuma , Fernando Rivadeneira , Blair H Smith , John M Starr , Henning Tiemeier , Nicholas J Timpson , Maciej Trzaskowski , André G Uitterlinden , Frank C Verhulst , Mary E Ward , Margaret J Wright , George Davey Smith , Ian J Deary , Magnus Johannesson , Robert Plomin , Peter M Visscher , Daniel J Benjamin , David Cesarini , Philipp D Koellinger

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.

Science     Cornelius A Rietveld , Sarah E Medland , Jaime Derringer , Jian Yang , Tõnu Esko , Nicolas W Martin , Harm-Jan Westra , Konstantin Shakhbazov , Abdel Abdellaoui , Arpana Agrawal , Eva Albrecht , Behrooz Z Alizadeh , Najaf Amin , John Barnard , Sebastian E Baumeister , Kelly S Benke , Lawrence F Bielak , Jeffrey A Boatman , Patricia A Boyle , Gail Davies , Christiaan de Leeuw , Niina Eklund , Daniel S Evans , Rudolf Ferhmann , Krista Fischer , Christian Gieger , HÃ¥kon K Gjessing , Sara Hägg , Jennifer R Harris , Caroline Hayward , Christina Holzapfel , Carla A Ibrahim-Verbaas , Erik Ingelsson , Bo Jacobsson , Peter K Joshi , Astanand Jugessur , Marika Kaakinen , Stavroula Kanoni , Juha Karjalainen , Ivana Kolcic , Kati Kristiansson , Zoltán Kutalik , Jari Lahti , Sang H Lee , Peng Lin , Penelope A Lind , Yongmei Liu , Kurt Lohman , Marisa Loitfelder , George McMahon , Pedro Marques Vidal , Osorio Meirelles , Lili Milani , Ronny Myhre , Marja-Liisa Nuotio , Christopher J Oldmeadow , Katja E Petrovic , Wouter J Peyrot , Ozren Polasek , Lydia Quaye , Eva Reinmaa , John P Rice , Thais S Rizzi , Helena Schmidt , Reinhold Schmidt , Albert V Smith , Jennifer A Smith , Toshiko Tanaka , Antonio Terracciano , Matthijs J H M van der Loos , Veronique Vitart , Henry Völzke , Jürgen Wellmann , Lei Yu , Wei Zhao , Jüri Allik , John R Attia , Stefania Bandinelli , François Bastardot , Jonathan Beauchamp , David A Bennett , Klaus Berger , Laura J Bierut , Dorret I Boomsma , Ute Bültmann , Harry Campbell , Christopher F Chabris , Lynn Cherkas , Mina K Chung , Francesco Cucca , Mariza de Andrade , Philip L De Jager , Jan-Emmanuel De Neve , Ian J Deary , George V Dedoussis , Panos Deloukas , Maria Dimitriou , Guðny Eiríksdóttir , Martin F Elderson , Johan G Eriksson , David M Evans , Jessica D Faul , Luigi Ferrucci , Melissa E Garcia , Henrik Grönberg , Vilmundur Guðnason , Per Hall , Juliette M Harris , Tamara B Harris , Nicholas D Hastie , Andrew C Heath , Dena G Hernandez , Wolfgang Hoffmann , Adriaan Hofman , Rolf Holle , Elizabeth G Holliday , Jouke-Jan Hottenga , William G Iacono , Thomas Illig , Marjo-Riitta Järvelin , Mika Kähönen , Jaakko Kaprio , Robert M Kirkpatrick , Matthew Kowgier , Antti Latvala , Lenore J Launer , Debbie A Lawlor , Terho Lehtimäki , Jingmei Li , Paul Lichtenstein , Peter Lichtner , David C Liewald , Pamela A Madden , Patrik K E Magnusson , Tomi E Mäkinen , Marco Masala , Matt McGue , Andres Metspalu , Andreas Mielck , Michael B Miller , Grant W Montgomery , Sutapa Mukherjee , Dale R Nyholt , Ben A Oostra , Lyle J Palmer , Aarno Palotie , Brenda W J H Penninx , Markus Perola , Patricia A Peyser , Martin Preisig , Katri Räikkönen , Olli T Raitakari , Anu Realo , Susan M Ring , Samuli Ripatti , Fernando Rivadeneira , Igor Rudan , Aldo Rustichini , Veikko Salomaa , Antti-Pekka Sarin , David Schlessinger , Rodney J Scott , Harold Snieder , Beate St Pourcain , John M Starr , Jae Hoon Sul , Ida Surakka , Rauli Svento , Alexander Teumer , LifeLines Cohort Study , Henning Tiemeier , Frank J A van Rooij , David R Van Wagoner , Erkki Vartiainen , Jorma Viikari , Peter Vollenweider , Judith M Vonk , Gérard Waeber , David R Weir , H-Erich Wichmann , Elisabeth Widen , Gonneke Willemsen , James F Wilson , Alan F Wright , Dalton Conley , George Davey-Smith , Lude Franke , Patrick J F Groenen , Albert Hofman , Magnus Johannesson , Sharon L R Kardia , Robert F Krueger , David Laibson , Nicholas G Martin , Michelle N Meyer , Danielle Posthuma , A Roy Thurik , Nicholas J Timpson , André G Uitterlinden , Cornelia M van Duijn , Peter M Visscher , Daniel J Benjamin , David Cesarini , Philipp D Koellinger

Genome-wide association studies identify four ER negative-specific breast cancer risk loci.

Nat Genet     Montserrat Garcia-Closas , Fergus J Couch , Sara Lindstrom , Kyriaki Michailidou , Marjanka K Schmidt , Mark N Brook , Nick Orr , Suhn Kyong Rhie , Elio Riboli , Heather S Feigelson , Loic Le Marchand , Julie E Buring , Diana Eccles , Penelope Miron , Peter A Fasching , Hiltrud Brauch , Jenny Chang-Claude , Jane Carpenter , Andrew K Godwin , Heli Nevanlinna , Graham G Giles , Angela Cox , John L Hopper , Manjeet K Bolla , Qin Wang , Joe Dennis , Ed Dicks , Will J Howat , Nils Schoof , Stig E Bojesen , Diether Lambrechts , Annegien Broeks , Irene L Andrulis , Pascal Guénel , Barbara Burwinkel , Elinor J Sawyer , Antoinette Hollestelle , Olivia Fletcher , Robert Winqvist , Hermann Brenner , Arto Mannermaa , Ute Hamann , Alfons Meindl , Annika Lindblom , Wei Zheng , Peter Devillee , Mark S Goldberg , Jan Lubinski , Vessela Kristensen , Anthony Swerdlow , Hoda Anton-Culver , Thilo Dörk , Kenneth Muir , Keitaro Matsuo , Anna H Wu , Paolo Radice , Soo Hwang Teo , Xiao-Ou Shu , William Blot , Daehee Kang , Mikael Hartman , Suleeporn Sangrajrang , Chen-Yang Shen , Melissa C Southey , Daniel J Park , Fleur Hammet , Jennifer Stone , Laura J Van't Veer , Emiel J Rutgers , Artitaya Lophatananon , Sarah Stewart-Brown , Pornthep Siriwanarangsan , Julian Peto , Michael G Schrauder , Arif B Ekici , Matthias W Beckmann , Isabel Dos Santos Silva , Nichola Johnson , Helen Warren , Ian Tomlinson , Michael J Kerin , Nicola Miller , Federick Marme , Andreas Schneeweiss , Christof Sohn , Therese Truong , Pierre Laurent-Puig , Pierre Kerbrat , Børge G Nordestgaard , Sune F Nielsen , Henrik Flyger , Roger L Milne , Jose Ignacio Arias Perez , Primitiva Menéndez , Heiko Müller , Volker Arndt , Christa Stegmaier , Peter Lichtner , Magdalena Lochmann , Christina Justenhoven , Yon-Dschun Ko , Gene ENvironmental Interaction and breast CAncer (GENICA) Network , Taru A Muranen , Kristiina Aittomäki , Carl Blomqvist , Dario Greco , Tuomas Heikkinen , Hidemi Ito , Hiroji Iwata , Yasushi Yatabe , Natalia N Antonenkova , Sara Margolin , Vesa Kataja , Veli-Matti Kosma , Jaana M Hartikainen , Rosemary Balleine , kConFab Investigators , Chiu-Chen Tseng , David Van Den Berg , Daniel O Stram , Patrick Neven , Anne-Sophie Dieudonné , Karin Leunen , Anja Rudolph , Stefan Nickels , Dieter Flesch-Janys , Paolo Peterlongo , Bernard Peissel , Loris Bernard , Janet E Olson , Xianshu Wang , Kristen Stevens , Gianluca Severi , Laura Baglietto , Catriona McLean , Gerhard A Coetzee , Ye Feng , Brian E Henderson , Fredrick Schumacher , Natalia V Bogdanova , France Labrèche , Martine Dumont , Cheng Har Yip , Nur Aishah Mohd Taib , Ching-Yu Cheng , Martha Shrubsole , Jirong Long , Katri Pylkäs , Arja Jukkola-Vuorinen , Saila Kauppila , Julia A Knight , Gord Glendon , Anna Marie Mulligan , Robertus A E M Tollenaar , Caroline M Seynaeve , Mieke Kriege , Maartje J Hooning , Ans M W van den Ouweland , Carolien H M van Deurzen , Wei Lu , Yu-Tang Gao , Hui Cai , Sabapathy P Balasubramanian , Simon S Cross , Malcolm W R Reed , Lisa Signorello , Qiuyin Cai , Mitul Shah , Hui Miao , Ching Wan Chan , Kee Seng Chia , Anna Jakubowska , Katarzyna Jaworska , Katarzyna Durda , Chia-Ni Hsiung , Pei-Ei Wu , Jyh-Cherng Yu , Alan Ashworth , Michael Jones , Daniel C Tessier , Anna González-Neira , Guillermo Pita , M Rosario Alonso , Daniel Vincent , Francois Bacot , Christine B Ambrosone , Elisa V Bandera , Esther M John , Gary K Chen , Jennifer J Hu , Jorge L Rodriguez-Gil , Leslie Bernstein , Michael F Press , Regina G Ziegler , Robert M Millikan , Sandra L Deming-Halverson , Sarah Nyante , Sue A Ingles , Quinten Waisfisz , Helen Tsimiklis , Enes Makalic , Daniel Schmidt , Minh Bui , Lorna Gibson , Bertram Müller-Myhsok , Rita K Schmutzler , Rebecca Hein , Norbert Dahmen , Lars Beckmann , Kirsimari Aaltonen , Kamila Czene , Astrid Irwanto , Jianjun Liu , Clare Turnbull , Familial Breast Cancer Study (FBCS) , Nazneen Rahman , Hanne Meijers-Heijboer , Andre G Uitterlinden , Fernando Rivadeneira , Australian Breast Cancer Tissue Bank (ABCTB) Investigators , Curtis Olswold , Susan Slager , Robert Pilarski , Foluso Ademuyiwa , Irene Konstantopoulou , Nicholas G Martin , Grant W Montgomery , Dennis J Slamon , Claudia Rauh , Michael P Lux , Sebastian M Jud , Thomas Bruning , Joellen Weaver , Priyanka Sharma , Harsh Pathak , Will Tapper , Sue Gerty , Lorraine Durcan , Dimitrios Trichopoulos , Rosario Tumino , Petra H Peeters , Rudolf Kaaks , Daniele Campa , Federico Canzian , Elisabete Weiderpass , Mattias Johansson , Kay-Tee Khaw , Ruth Travis , Françoise Clavel-Chapelon , Laurence N Kolonel , Constance Chen , Andy Beck , Susan E Hankinson , Christine D Berg , Robert N Hoover , Jolanta Lissowska , Jonine D Figueroa , Daniel I Chasman , Mia M Gaudet , W Ryan Diver , Walter C Willett , David J Hunter , Jacques Simard , Javier Benitez , Alison M Dunning , Mark E Sherman , Georgia Chenevix-Trench , Stephen J Chanock , Per Hall , Paul D P Pharoah , Celine Vachon , Douglas F Easton , Christopher A Haiman , Peter Kraft

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.

Nat Genet     Rosalind A Eeles , Ali Amin Al Olama , Sara Benlloch , Edward J Saunders , Daniel A Leongamornlert , Malgorzata Tymrakiewicz , Maya Ghoussaini , Craig Luccarini , Joe Dennis , Sarah Jugurnauth-Little , Tokhir Dadaev , David E Neal , Freddie C Hamdy , Jenny L Donovan , Ken Muir , Graham G Giles , Gianluca Severi , Fredrik Wiklund , Henrik Gronberg , Christopher A Haiman , Fredrick Schumacher , Brian E Henderson , Loic Le Marchand , Sara Lindstrom , Peter Kraft , David J Hunter , Susan Gapstur , Stephen J Chanock , Sonja I Berndt , Demetrius Albanes , Gerald Andriole , Johanna Schleutker , Maren Weischer , Federico Canzian , Elio Riboli , Tim J Key , Ruth C Travis , Daniele Campa , Sue A Ingles , Esther M John , Richard B Hayes , Paul D P Pharoah , Nora Pashayan , Kay-Tee Khaw , Janet L Stanford , Elaine A Ostrander , Lisa B Signorello , Stephen N Thibodeau , Dan Schaid , Christiane Maier , Walther Vogel , Adam S Kibel , Cezary Cybulski , Jan Lubinski , Lisa Cannon-Albright , Hermann Brenner , Jong Y Park , Radka Kaneva , Jyotsna Batra , Amanda B Spurdle , Judith A Clements , Manuel R Teixeira , Ed Dicks , Andrew Lee , Alison M Dunning , Caroline Baynes , Don Conroy , Melanie J Maranian , Shahana Ahmed , Koveela Govindasami , Michelle Guy , Rosemary A Wilkinson , Emma J Sawyer , Angela Morgan , David P Dearnaley , Alan Horwich , Robert A Huddart , Vincent S Khoo , Christopher C Parker , Nicholas J Van As , Christopher J Woodhouse , Alan Thompson , Tim Dudderidge , Chris Ogden , Colin S Cooper , Artitaya Lophatananon , Angela Cox , Melissa C Southey , John L Hopper , Dallas R English , Markus Aly , Jan Adolfsson , Jiangfeng Xu , Siqun L Zheng , Meredith Yeager , Rudolf Kaaks , W Ryan Diver , Mia M Gaudet , Mariana C Stern , Roman Corral , Amit D Joshi , Ahva Shahabi , Tiina Wahlfors , Teuvo L J Tammela , Anssi Auvinen , Jarmo Virtamo , Peter Klarskov , Børge G Nordestgaard , M Andreas Røder , Sune F Nielsen , Stig E Bojesen , Afshan Siddiq , Liesel M Fitzgerald , Suzanne Kolb , Erika M Kwon , Danielle M Karyadi , William J Blot , Wei Zheng , Qiuyin Cai , Shannon K McDonnell , Antje E Rinckleb , Bettina Drake , Graham Colditz , Dominika Wokolorczyk , Robert A Stephenson , Craig Teerlink , Heiko Muller , Dietrich Rothenbacher , Thomas A Sellers , Hui-Yi Lin , Chavdar Slavov , Vanio Mitev , Felicity Lose , Srilakshmi Srinivasan , Sofia Maia , Paula Paulo , Ethan Lange , Kathleen A Cooney , Antonis C Antoniou , Daniel Vincent , François Bacot , Daniel C Tessier , COGS–Cancer Research UK GWAS–ELLIPSE (part of GAME-ON) Initiative , Australian Prostate Cancer Bioresource , UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology , UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators , PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium , Zsofia Kote-Jarai , Douglas F Easton

Toward an understanding of the protein interaction network of the human liver.

Mol. Syst. Biol.     Jian Wang , Keke Huo , Lixin Ma , Liujun Tang , Dong Li , Xiaobi Huang , Yanzhi Yuan , Chunhua Li , Wei Wang , Wei Guan , Hui Chen , Chaozhi Jin , Juncheng Wei , Wanqiao Zhang , Yongsheng Yang , Qiongming Liu , Ying Zhou , Cuili Zhang , Zhihao Wu , Wangxiang Xu , Ying Zhang , Tao Liu , Donghui Yu , Yaping Zhang , Liang Chen , Dewu Zhu , Xing Zhong , Lixin Kang , Xiang Gan , Xiaolan Yu , Qi Ma , Jing Yan , Li Zhou , Zhongyang Liu , Yunping Zhu , Tao Zhou , Fuchu He , Xiaoming Yang

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Mol. Med.     Jed E Rose , Frédérique M Behm , Tomas Drgon , Catherine Johnson , George R Uhl

The DNA sequence and biological annotation of human chromosome 1.

Nature     S G Gregory , K F Barlow , K E McLay , R Kaul , D Swarbreck , A Dunham , C E Scott , K L Howe , K Woodfine , C C A Spencer , M C Jones , C Gillson , S Searle , Y Zhou , F Kokocinski , L McDonald , R Evans , K Phillips , A Atkinson , R Cooper , C Jones , R E Hall , T D Andrews , C Lloyd , R Ainscough , J P Almeida , K D Ambrose , F Anderson , R W Andrew , R I S Ashwell , K Aubin , A K Babbage , C L Bagguley , J Bailey , H Beasley , G Bethel , C P Bird , S Bray-Allen , J Y Brown , A J Brown , D Buckley , J Burton , J Bye , C Carder , J C Chapman , S Y Clark , G Clarke , C Clee , V Cobley , R E Collier , N Corby , G J Coville , J Davies , R Deadman , M Dunn , M Earthrowl , A G Ellington , H Errington , A Frankish , J Frankland , L French , P Garner , J Garnett , L Gay , M R J Ghori , R Gibson , L M Gilby , W Gillett , R J Glithero , D V Grafham , C Griffiths , S Griffiths-Jones , R Grocock , S Hammond , E S I Harrison , E Hart , E Haugen , P D Heath , S Holmes , K Holt , P J Howden , A R Hunt , S E Hunt , G Hunter , J Isherwood , R James , C Johnson , D Johnson , A Joy , M Kay , J K Kershaw , M Kibukawa , A M Kimberley , A King , A J Knights , H Lad , G Laird , S Lawlor , D A Leongamornlert , D M Lloyd , J Loveland , J Lovell , M J Lush , R Lyne , S Martin , M Mashreghi-Mohammadi , L Matthews , N S W Matthews , S McLaren , S Milne , S Mistry , M J F Moore , T Nickerson , C N O'Dell , K Oliver , A Palmeiri , S A Palmer , A Parker , D Patel , A V Pearce , A I Peck , S Pelan , K Phelps , B J Phillimore , R Plumb , J Rajan , C Raymond , G Rouse , C Saenphimmachak , H K Sehra , E Sheridan , R Shownkeen , S Sims , C D Skuce , M Smith , C Steward , S Subramanian , N Sycamore , A Tracey , A Tromans , Z Van Helmond , M Wall , J M Wallis , S White , S L Whitehead , J E Wilkinson , D L Willey , H Williams , L Wilming , P W Wray , Z Wu , A Coulson , M Vaudin , J E Sulston , R Durbin , T Hubbard , R Wooster , I Dunham , N P Carter , G McVean , M T Ross , J Harrow , M V Olson , S Beck , J Rogers , D R Bentley , R Banerjee , S P Bryant , D C Burford , W D H Burrill , S M Clegg , P Dhami , O Dovey , L M Faulkner , S M Gribble , C F Langford , R D Pandian , K M Porter , E Prigmore