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104394 E2f4

104394

E2f4

E2F transcription factor 4

protein-coding

Mus musculus

基因描述

Type Description
Definition E2F transcription factor 4

研究结论

Date Results Publications
2020-04-25 12:37:00 Overexpressing p130 or E2F4 in mMSCs could further improve the injured structure and function of epithelial cells in the lungs of ARDS mice as a result of improved differentiation of mMSCs into epithelial cells. 30841904
2019-12-14 12:15:00 E2F1 and E2F4 regulated Cited2 expression in neurons after stroke-related insults. Taken together, these results indicate that the E2F-Cited2 regulatory pathway is critically involved in stroke injury. 30967472
2019-09-28 10:22:00 E2F4 is important for the proliferation and the survival of mouse embryonic stem cells. 31270324
2018-12-22 10:12:00 E2f4 forms apical cytoplasmic organizing centres for assembly and nucleation of deuterosomes. Using genetically altered mice and E2F4 mutant proteins we demonstrate that centriole amplification is crucially dependent on these organizing centres and that, without cytoplasmic E2f4, deuterosomes are not assembled, halting multiciliogenesis 28675157
2016-10-22 10:52:00 E2f4 and E2f5 display overlapping roles in controlling the normal development of the male reproductive system. 26825228

名称对应

Type IDs
Synonymous 2010111M04Rik, AI427446
Gene
UniProtKB-ID: E2F4_MOUSE
UniprotKB: Q8R0K9
UniParc: UPI0000027C64
EMBL: BC027048, BC023859, AK145950, AK157028, BC026649
Ensembl: ENSMUSG00000014859
KO: mmu:104394
Nucleutide sequences
EMBL-CDS: AAH23859.1, BAE33937.1, AAH27048.1, AAH26649.1, BAE26778.1
Ensembl_TRS: ENSMUST00000015003
Protein sequencees
Ensembl_PRO: ENSMUSP00000015003
RefSeq: NP_683754.1
Others
UniRef100: UniRef100_Q8R0K9
UniRef90: UniRef90_Q8R0K9
UniRef50: UniRef50_Q16254
UniGene: Mm.34554
CCDS: CCDS40456.1

全选

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研究热度

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