| Type | Description |
|---|---|
| Definition | CDC42 effector protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-22 11:16:00 | Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1-5 proteins (Cdc42EP1-5), including cytoskeletal remodelling and signalling. | 27913681 |
| 2011-06-04 10:51:00 | CDC42EP2 is upregulated in human PDLCs subjected to tensile stress related to mechano-induced cell cycle arrest. | 20934684 |
| 2010-01-21 00:00:00 | activations of Rac1 and Cdc42 are involved in the hypoxia-induced production of angiogenesis-promoting factors and tumor suppressors, and suggest that the Rho family GTPases Rac1 and Cdc42 may contribute to the hypoxia-mediated angiogenesis. | 16395716 |
| Type | IDs |
|---|---|
| Synonymous | BORG1, CEP2 |
| Gene |
UniProtKB-ID:
BORG1_HUMAN
UniprotKB:
O14613
UniParc:
UPI000000D7F5
EMBL:
BC075834,
AF548903,
BC022337,
BT020004,
AK315444,
AF001436,
AF163840,
AF098290
Ensembl:
ENSG00000149798
KO:
hsa:10435
|
| Nucleutide sequences |
EMBL-CDS:
AAN39381.1,
BAG37832.1,
AAD48784.1,
AAH22337.1,
AAV38807.1,
AAB81206.1,
AAD16185.1,
AAH75834.1
Ensembl_TRS:
ENST00000279249,
ENST00000533419
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000279249,
ENSP00000431660
RefSeq:
NP_006770.1
|
| Others |
UniRef100:
UniRef100_O14613
UniRef90:
UniRef90_O14613
UniRef50:
UniRef50_O14613
UniGene:
Hs.343380
CCDS:
CCDS8099.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31478661 |
J. Proteome Res. Luiz E Silva , Renan C Souza , Eduardo S Kitano , Lucas F Monteiro , Leo K Iwai , Fabio L Forti |
2019-10-04 | - |
| 31413325 |
HENA, heterogeneous network-based data set for Alzheimer's disease. Sci Data Elena Sügis , Jerome Dauvillier , Anna Leontjeva , Priit Adler , Valerie Hindie , Thomas Moncion , Vincent Collura , Rachel Daudin , Yann Loe-Mie , Yann Herault , Jean-Charles Lambert , Henning Hermjakob , Tal Pupko , Jean-Christophe Rain , Ioannis Xenarios , Jaak Vilo , Michel Simonneau , Hedi Peterson |
2019-08-14 | - |
| 30639242 |
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2. Mol. Cell Joanna R Kovalski , Aparna Bhaduri , Ashley M Zehnder , Poornima H Neela , Yonglu Che , Glenn G Wozniak , Paul A Khavari |
2019-02-21 | - |
| 29507755 |
Cell Discov Yanan Yue , Jun Liu , Xiaolong Cui , Jie Cao , Guanzheng Luo , Zezhou Zhang , Tao Cheng , Minsong Gao , Xiao Shu , Honghui Ma , Fengqin Wang , Xinxia Wang , Bin Shen , Yizhen Wang , Xinhua Feng , Chuan He , Jianzhao Liu |
2018-01-01 | - |
| 27913681 |
The Borg family of Cdc42 effector proteins Cdc42EP1-5. Biochem Soc Trans Aaron J Farrugia , Fernando Calvo |
2016-12-15 | - |
| 26871637 |
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell Xinping Yang , Jasmin Coulombe-Huntington , Shuli Kang , Gloria M Sheynkman , Tong Hao , Aaron Richardson , Song Sun , Fan Yang , Yun A Shen , Ryan R Murray , Kerstin Spirohn , Bridget E Begg , Miquel Duran-Frigola , Andrew MacWilliams , Samuel J Pevzner , Quan Zhong , Shelly A Trigg , Stanley Tam , Lila Ghamsari , Nidhi Sahni , Song Yi , Maria D Rodriguez , Dawit Balcha , Guihong Tan , Michael Costanzo , Brenda Andrews , Charles Boone , Xianghong J Zhou , Kourosh Salehi-Ashtiani , Benoit Charloteaux , Alyce A Chen , Michael A Calderwood , Patrick Aloy , Frederick P Roth , David E Hill , Lilia M Iakoucheva , Yu Xia , Marc Vidal |
2016-02-11 |
USH1C,
PQBP1,
OPTN,
RBM5,
CDK5,
CDK7,
RABEPK,
SRRM1,
NOD1,
CD2BP2,
RBM14,
HAX1,
SLC30A9,
STK25,
SEMA4F,
SLC19A2,
CETP,
SRSF10,
SEPT9,
ALDH1L1,
RCC1,
LDB3,
AKAP10,
SEC63,
PHF21B,
HELQ,
CKB,
ERCC8,
CLCN2,
ZFYVE27,
CLPTM1,
TTC8,
C15orf40,
COL1A2,
BBS5,
ACMSD,
DNAJC19,
CPA2,
C7orf34,
CRH,
CRK,
RDH12,
MIPOL1,
ZNF688,
SLC25A10,
NKX2-5,
CTNS,
CTSD,
UPP2,
CYBB,
CYP11A1,
TSTD2,
DAO,
REM2,
DYX1C1,
DCN,
DDC,
GLIS3,
DGUOK,
DHCR7,
DMD,
E2F6,
TYMP,
EGR2,
FLCN,
EPHX1,
EYA4,
ETFA,
ETV6,
FANCC,
FANCG,
EFEMP1,
MICU2,
ZUFSP,
FCGR3A,
ABCB7,
FGA,
FGFR1,
FH,
DOLK,
KIAA0907,
ARHGEF15,
SETX,
ARHGAP26,
SPG20,
FMO3,
ETHE1,
SLC39A14,
CDK20,
SMUG1,
FXN,
FTSJ1,
MCM9,
GABRA2,
GAD1,
SUMF2,
GALT,
UNC50,
FBXO8
|
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 24927181 |
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. Nat Commun Alexander A Navarini , Michael A Simpson , Michael Weale , Jo Knight , Isabelle Carlavan , Pascale Reiniche , David A Burden , Alison Layton , Veronique Bataille , Michael Allen , Robert Pleass , Andrew Pink , Daniel Creamer , John English , Stephanie Munn , Shernaz Walton , Acne Genetic Study Group , Carolyn Willis , Sophie Déret , Johannes J Voegel , Tim Spector , Catherine H Smith , Richard C Trembath , Jonathan N Barker |
2014-06-13 | - |
| 21988832 |
Toward an understanding of the protein interaction network of the human liver. Mol. Syst. Biol. Jian Wang , Keke Huo , Lixin Ma , Liujun Tang , Dong Li , Xiaobi Huang , Yanzhi Yuan , Chunhua Li , Wei Wang , Wei Guan , Hui Chen , Chaozhi Jin , Juncheng Wei , Wanqiao Zhang , Yongsheng Yang , Qiongming Liu , Ying Zhou , Cuili Zhang , Zhihao Wu , Wangxiang Xu , Ying Zhang , Tao Liu , Donghui Yu , Yaping Zhang , Liang Chen , Dewu Zhu , Xing Zhong , Lixin Kang , Xiang Gan , Xiaolan Yu , Qi Ma , Jing Yan , Li Zhou , Zhongyang Liu , Yunping Zhu , Tao Zhou , Fuchu He , Xiaoming Yang |
2011-10-11 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员