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104346 Gas8

104346

Gas8

growth arrest specific 8

protein-coding

Mus musculus

基因描述

Type Description
Definition growth arrest specific 8

研究结论

Date Results Publications
2017-03-25 11:50:00 Here, we generate the first mouse with a Gas8 mutation and show that it causes severe Primary Ciliary Dyskinesia (PCD)phenotypes; however, there were no overt Hh pathway phenotypes. In addition, we identified two human patients with missense variants in Gas8 27472056
2011-10-15 11:29:00 results identify Gas8 as a positive regulator of Hh signaling that cooperates with GRK2 to control Smo signaling 21659505
2010-01-21 00:00:00 a growth arrest specific gene regulated during male gametogensis 11751847
2010-01-21 00:00:00 Gas11, the mammalian trypanin/PF2 homologue, associates with microtubules in vitro and in vivo. 17366626
2010-01-21 00:00:00 Gas8 was specifically interacted with the GTP-bound form of Rab3B and co-localized with Rab3B at the Golgi in NIH 3T3 cells 18396146

名称对应

Type IDs
Synonymous Gas11
Gene
UniProtKB-ID: DRC4_MOUSE, Q49MD7_MOUSE
UniprotKB: Q60779, Q49MD7
UniParc: UPI00001B3DE1
EMBL: U19859, AY692443, BC003779
Ensembl: ENSMUSG00000040220
KO: mmu:104346
Nucleutide sequences
EMBL-CDS: AAH03779.2, AAA85258.1, AAW47235.1
Ensembl_TRS: ENSMUST00000093043
Protein sequencees
Ensembl_PRO: ENSMUSP00000090730
RefSeq: XP_006530614.1, NP_061343.2, XP_006530615.1, XP_030099088.1, XP_030099089.1
Others
UniRef100: UniRef100_Q60779
UniRef90: UniRef90_Q60779
UniRef50: UniRef50_O95995
UniGene: Mm.117265
CCDS: CCDS40512.1

全选

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