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104271 Tex15

104271

Tex15

testis expressed gene 15

protein-coding

Mus musculus

基因描述

Type Description
Definition testis expressed gene 15

研究结论

Date Results Publications
2020-11-21 13:22:00 TEX15 associates with MILI and silences transposable elements in male germ cells. 32381626
2020-09-12 16:03:00 TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing. 32719317
2020-05-12 16:42:00 Loss of TEX15 leads to DNA hypomethylation and de-silencing of transposable elements, at a level comparable to loss of MILI or DNMT3C but not MIWI2. TEX15 is associated with MILI in testis. piRNA biogenesis is intact in TEX15-deficient male germ cells. 32381626
2010-01-21 00:00:00 Based on these data, we propose that TEX15 regulates the loading of DNA repair proteins onto sites of DSBs and, thus, its absence causes a failure in meiotic recombination. 18283110
2008-04-10 10:12:00 Tex15 is essential for male meiosis and for chromosomal synapsis. DNA double-strand breaks (DSBs) are formed but not repaired in Tex15-deficient males. 18283110

名称对应

Type IDs
Synonymous 2210014E14Rik, AL022622, AU022940
Gene
UniProtKB-ID: TEX15_MOUSE
UniprotKB: F8VPN2
UniParc: UPI00074481DB, UPI0000564848
EMBL: AK132667, AF285589, AK143304, AC117807, AC139025
Ensembl: ENSMUSG00000009628
KO: mmu:104271
Nucleutide sequences
EMBL-CDS: BAE21290.1, AAK31968.1, BAE25339.1
Ensembl_TRS: ENSMUST00000009772
Protein sequencees
Ensembl_PRO: ENSMUSP00000009772
RefSeq: XP_006509038.1, XP_011240408.1, XP_006509040.1, XP_006509039.1, NP_113551.2
Others
UniRef100: UniRef100_F8VPN2
UniRef90: UniRef90_F8VPN2
UniRef50: UniRef50_F8VPN2
UniGene: Mm.280624, Mm.488030
CCDS: CCDS22232.1

全选

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