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104174 Gldc

104174

Gldc

glycine decarboxylase

protein-coding

Mus musculus

基因描述

Type Description
Definition glycine decarboxylase

研究结论

Date Results Publications
2020-11-21 13:13:00 Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase-deficient mice. 31794432
2017-10-07 10:32:00 Exencephaly and ventriculomegaly were detectable by High-frequency ultrasound in homozygous Gldc-deficient mouse embryos indicating this to be an effective tool to study CNS development. 28056489
2016-09-10 11:24:00 These studies support a direct relationship between p53 mutations and GLDC expression in B cell lymphoma. 26599272
2016-02-13 10:08:00 Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice through limiting supply of one-carbon units from mitochondrial folate metabolism. 25736695
2010-01-21 00:00:00 Results suggest that there is a direct correlation between ischemic injury and extracellular glycine concentration maintained by glycine decarboxylase and the glycine cleavage multienzyme system. 17510459

名称对应

Type IDs
Synonymous D030049L12Rik, D19Wsu57e, b2b2679Clo
Gene
UniProtKB-ID: GCSP_MOUSE
UniprotKB: Q91W43
UniParc: UPI0000029254
EMBL: BC017135
Ensembl: ENSMUSG00000024827
KO: mmu:104174
Nucleutide sequences
EMBL-CDS: AAH17135.1
Ensembl_TRS: ENSMUST00000025778
Protein sequencees
Ensembl_PRO: ENSMUSP00000025778
RefSeq: NP_613061.1
Others
UniRef100: UniRef100_Q91W43
UniRef90: UniRef90_Q91W43
UniRef50: UniRef50_P15505
UniGene: Mm.274852
CCDS: CCDS37956.1

全选

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研究热度

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