| Type | Description |
|---|---|
| Definition | spondin 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:23:00 | Study identified the extracelular matrix protein mindin in the secretome of prostate adenocarcinoma cells and show that mindin overexpression in human and mouse TRAMP-C1-induced prostate tumors correlates with upregulated levels of bone-related genes in the tumorigenic prostate tissues. Mindin silencing decreased osteomimicry in adenocarcinoma cells and in the prostate tumor mice model. | 31168562 |
| 2019-06-15 11:20:00 | High SPON2 expression is associated with hepatocellular carcinoma. | 30318967 |
| 2019-05-25 11:11:00 | Matricellular protein SPON2 acts as an HCC suppressor and utilizes distinct signaling events to perform dual functions in HCC microenvironment | 29440144 |
| 2019-03-23 10:25:00 | spondin-2 might be a novel therapeutic target and prognostic biomarker for squamous cell carcinoma patients | 30527359 |
| 2018-10-13 10:27:00 | Egr-1 regulates mindin expression by directly binding to the mindin promoter; mindin suppresses colon cancer progression by blocking angiogenesis. | 28991232 |
| Type | IDs |
|---|---|
| Synonymous | DIL-1, DIL1, M-SPONDIN, MINDIN |
| Gene |
UniProtKB-ID:
SPON2_HUMAN
UniprotKB:
Q9BUD6
UniParc:
UPI0001E88E77
EMBL:
AK074770,
AC092535,
BC002707,
AK074618,
AB027466,
AY358948,
BC036341,
CH471131
Ensembl:
ENSG00000159674
KO:
hsa:10417
|
| Nucleutide sequences |
EMBL-CDS:
BAC11196.1,
BAA85892.1,
EAW82604.1,
AAH36341.1,
AAQ89307.1,
BAC11092.1,
AAY40988.1,
AAH02707.1,
EAW82606.1
Gene_ORFName:
UNQ435/PRO866
Ensembl_TRS:
ENST00000617421,
ENST00000431380,
ENST00000290902
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000483599,
ENSP00000394832,
ENSP00000290902
RefSeq:
NP_001185950.2,
NP_036577.2,
NP_001121797.2
|
| Others |
UniRef100:
UniRef100_Q9BUD6
UniRef90:
UniRef90_Q9BUD6
UniRef50:
UniRef50_Q9BUD6
UniGene:
Hs.302963,
Hs.635350,
Hs.736956
CCDS:
CCDS3347.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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