| Type | Description |
|---|---|
| Definition | Rap guanine nucleotide exchange factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:55:00 | LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient. | 33362237 |
| 2021-01-09 13:32:00 | Downregulation of Epac Reduces Fibrosis and Induces Apoptosis Through Akt Signaling in Human Keloid Fibroblasts. | 32890866 |
| 2020-10-24 13:55:00 | Dysfunctional EAT thickness may promote maladaptive heart remodeling in CVD patients through the ST2-IL33 system, directly related to EPAC protein expression. | 31316160 |
| 2020-09-19 16:30:00 | Conformational States of Exchange Protein Directly Activated by cAMP (EPAC1) Revealed by Ensemble Modeling and Integrative | 31877746 |
| 2019-11-23 10:57:00 | Coxiella burnetii is a Gram negative bacterium that survives and grows in a large Coxiella replicative vacuole (CRV), which displays lysosomal and autophagic features. This report presents evidence that both, EPAC and its downstream effector Rap2b, were recruited to the CRV. | 30763357 |
| Type | IDs |
|---|---|
| Synonymous | CAMP-GEFI, EPAC, EPAC1, HSU79275, bcm910 |
| Gene |
UniProtKB-ID:
RPGF3_HUMAN,
Q99777_HUMAN
UniprotKB:
O95398,
Q99777
UniParc:
UPI0000E595C5,
UPI000006F1CF,
UPI0000DBEEF5,
UPI0000406B36
EMBL:
U79275,
AC137054,
AF103905,
U78169,
CH471111,
BC017728,
U78168,
AK290230,
AC004241
Ensembl:
ENSG00000079337
KO:
hsa:10411
|
| Nucleutide sequences |
EMBL-CDS:
BAF82919.1,
EAW57944.1,
AAD12740.1,
AAH17728.2,
AAD02890.1,
AAC83381.1,
AAB50216.1
Ensembl_TRS:
ENST00000389212,
ENST00000395358,
ENST00000405493,
ENST00000449771,
ENST00000549151
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000373864,
ENSP00000384521,
ENSP00000378764,
ENSP00000448619,
ENSP00000395708
RefSeq:
NP_001092002.1,
NP_006096.2,
XP_011536057.1,
XP_005268628.1,
NP_001092001.2,
XP_024304563.1,
XP_011536060.1,
XP_011536054.1,
XP_016874177.1
|
| Others |
UniRef100:
UniRef100_Q99777,
UniRef100_O95398
UniRef90:
UniRef90_Q99777,
UniRef90_O95398
UniRef50:
UniRef50_Q99777,
UniRef50_O95398
UniGene:
Hs.8578
CCDS:
CCDS41775.1,
CCDS31784.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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