| Type | Description |
|---|---|
| Definition | antisense Igf2r RNA |
| Date | Results | Publications |
|---|---|---|
| 2020-01-18 11:48:00 | Chromatin environments surrounding Xist, Airn, and Kcnq1ot1 suggest common mechanisms of PRC engagement and spreading. Our data indicate that lncRNA potency can be tightly linked to lncRNA abundance and that within lncRNA-targeted domains, PRCs are recruited to CGIs via lncRNA-independent mechanisms. | 31256989 |
| 2019-12-21 12:02:00 | Study showed that chromosome interactions between the Airn gene body and the Slc22a3 promoter are enriched on the maternal allele because Airn expression represses these interactions on the paternal allele. These interactions are not required to upregulate Slc22a3 expression on the maternal allele, indicating that they are not essential promoter- enhancer interactions; they may serve to place both loci in close promixity. | 31329595 |
| 2019-09-21 10:45:00 | In cardiomyocytes, silencing of Airn via siRNAs augmented cell death, vulnerability to cellular stress, and reduced cell migration. It also caused less binding of Igf2bp2 to other mRNAs and reduced translation of Igf2bp2 protein. Airn's binding partners were Igf2bp2 and Rpa1. | 29483092 |
| 2013-05-04 12:33:00 | Airn expression is both necessary and sufficient to silence Igf2r throughout embryonic stem cell differentiation. | 23444351 |
| 2012-12-22 10:28:00 | The results excluded a role for spliced and unspliced Airn lncRNA products and for Airn nuclear size and location in silencing Igf2r. Instead, silencing only required Airn transcriptional overlap of the Igf2r promoter, which interferes with RNA polymerase II recruitment in the absence of repressive chromatin. | 23239737 |
| Type | IDs |
|---|---|
| Synonymous | 2810051F02Rik, 2810434M15Rik, AI256653, AI597500, AW049873, Air, B930018I07Rik, D17Ertd663e, IGF2RAS |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees | |
| Others |
UniGene:
Mm.26553,
Mm.44983,
Mm.435560,
Mm.486805,
Mm.488586
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员