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10409 BASP1

10409

BASP1

brain abundant membrane attached signal protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition brain abundant membrane attached signal protein 1

研究结论

Date Results Publications
2021-02-06 13:56:00 The brain acid-soluble protein 1 (BASP1) interferes with the oncogenic capacity of MYC and its binding to calmodulin. 31944520
2019-11-30 10:57:00 Bioinformatic analysis and clinical data from our study suggest that BASP1 and its putative interaction partner WT1 can be used as biomarkers for predicting outcomes in pancreatic cancer patients. 30982764
2019-02-09 10:30:00 data suggest that BASP1 silencing via promoter methylation may be involved in A/E-mediated leukemogenesis and that BASP1 targeting may be an actionable therapeutic strategy in t(8;21) AML. 29674693
2018-02-17 11:44:00 data have identified BASP1 as an ERalpha cofactor that has a central role in the transcriptional and antitumourigenic effects of tamoxifen. 28492543
2017-09-23 13:08:00 we uncover a novel polymorphism, rs187843643 (OR = 1.96; 95% CI = [1.54, 2.48]; P = 3.53 x 10-8), associated with melanoma. The SNP rs187842643 lies within a noncoding RNA 177kb downstream of BASP1 (brain associated protein-1). We find that BASP1 expression is suppressed in melanoma as compared with benign nevi, providing additional evidence for a putative role in melanoma pathogenesis. 28212542

名称对应

Type IDs
Synonymous CAP-23, CAP23, NAP-22, NAP22
Gene
UniProtKB-ID: BASP1_HUMAN
UniprotKB: P80723
UniParc: UPI0000140E98, UPI00017A71A3
EMBL: CH471102, AK295995, AF039656, BT019341, BT019340, BC000518
Ensembl: ENSG00000176788
KO: hsa:10409
Nucleutide sequences
EMBL-CDS: EAX08012.1, AAH00518.1, EAX08013.1, AAV38147.1, BAG58770.1, AAC67374.1, AAV38148.1
Ensembl_TRS: ENST00000616743, ENST00000322611
Protein sequencees
Ensembl_PRO: ENSP00000482066, ENSP00000319281
RefSeq: NP_006308.3, NP_001258535.1
Others
UniRef100: UniRef100_P80723
UniRef90: UniRef90_P80723
UniRef50: UniRef50_P80723
UniGene: Hs.201641, Hs.646924
CCDS: CCDS3888.1

全选

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