| Type | Description |
|---|---|
| Definition | NDC80 kinetochore complex component |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 13:09:00 | nuclear division cycle 80, cyclin B2 and topoisomerase 2alpha may serve important roles in adrenocortical tumor development. | 30816525 |
| 2019-05-25 12:35:00 | High NDC80 expression is associated with colorectal cancer. | 29341479 |
| 2019-05-04 12:42:00 | Using pulldown assays with HeLa cell lysates and site-directed mutagenesis, this study shows that HEC1 is a bona fide substrate of the lysine acetyltransferase Tat-interacting protein, 60 kDa (TIP60) and that TIP60-mediated acetylation of HEC1 is essential for accurate chromosome segregation in mitosis. | 30409912 |
| 2019-03-16 10:12:00 | The results indicate that Sf3A2 and Prp31 directly regulate interactions among kinetochores, spindle microtubules and the Ndc80 complex in both Drosophila and human cells. | 30475206 |
| 2019-03-02 10:06:00 | NDC80 binding is modulated in a chromosome autonomous fashion over prometaphase and metaphase, and is predominantly regulated by centromere tension. | 30044223 |
| Type | IDs |
|---|---|
| Synonymous | HEC, HEC1, HsHec1, KNTC2, TID3, hsNDC80 |
| Gene |
UniProtKB-ID:
NDC80_HUMAN,
A8K031_HUMAN
UniprotKB:
O14777,
A8K031
UniParc:
UPI0000073C92
EMBL:
AK313184,
BC035617,
BC010171,
AK289396,
CH471113,
AF017790
Ensembl:
ENSG00000080986
KO:
hsa:10403
|
| Nucleutide sequences |
EMBL-CDS:
AAB80726.1,
EAX01697.1,
BAF82085.1,
AAH35617.1,
BAG36001.1,
EAX01696.1
Gene_ORFName:
hCG_38410
Ensembl_TRS:
ENST00000261597
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261597
RefSeq:
NP_006092.1
|
| Others |
UniRef100:
UniRef100_O14777
UniRef90:
UniRef90_O14777
UniRef50:
UniRef50_O14777
UniGene:
Hs.414407
CCDS:
CCDS11827.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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