| Type | Description |
|---|---|
| Definition | protein inhibitor of activated STAT 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:13:00 | Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer. | 32398867 |
| 2020-08-15 19:07:00 | miR-199a-5p promotes proliferation and metastasis and epithelial-mesenchymal transition through targeting PIAS3 in cervical carcinoma. | 30937952 |
| 2020-08-15 19:05:00 | PIAS genes as disease markers in bipolar disorder. | 30861611 |
| 2019-12-21 10:15:00 | Here we report that Csk is covalently modified by SUMO1 at lysine 53 (K53) both in vitro and in vivo. Treatment with hydrogen peroxide inhibited this modification to a certain extent, but PIAS3, identified as the main specific SUMO E3 ligase for Csk, could significantly enhance SUMO1-Csk level | 31125786 |
| 2019-11-23 12:36:00 | a positive feedback loop between miR-181b and that regulated the Warburg effect in colon cancer was also demonstrated. This study suggested axis as a novel target for colon cancer treatment. | 30054984 |
| Type | IDs |
|---|---|
| Synonymous | ZMIZ5 |
| Gene |
UniProtKB-ID:
PIAS3_HUMAN,
B3KNI3_HUMAN
UniprotKB:
Q9Y6X2,
B3KNI3
UniParc:
UPI0000158C32,
UPI0000150636
EMBL:
BC001154,
BC030556,
AK027557,
AB021868
Ensembl:
ENSG00000131788
KO:
hsa:10401
|
| Nucleutide sequences |
EMBL-CDS:
AAH30556.2,
AAH01154.2,
BAA78533.1,
BAG51345.1
Ensembl_TRS:
ENST00000393045
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376765
RefSeq:
NP_006090.2
|
| Others |
UniRef100:
UniRef100_B3KNI3,
UniRef100_Q9Y6X2
UniRef90:
UniRef90_O54714
UniRef50:
UniRef50_O54714
UniGene:
Hs.435761
CCDS:
CCDS72866.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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