Type | Description |
---|---|
Definition | adenosine deaminase RNA specific B1 |
Date | Results | Publications |
---|---|---|
2020-09-26 13:08:00 | Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition. | 32597966 |
2020-09-05 13:55:00 | ADAR2 Is Involved in Self and Nonself Recognition of Borna Disease Virus Genomic RNA in the Nucleus. | 31852792 |
2020-07-25 13:02:00 | that the mislocalization of ADAR2 in C9orf72 mediated amyotrophic lateral sclerosis/frontotemporal dementia is responsible for the alteration of RNA processing events that may impact vast cellular functions | 30945056 |
2020-07-18 12:04:00 | We also observe a dominance of long-range interactions within ADAR substrates and analyze differences between ADAR1 and ADAR2 editing substrates. Moreover, we unexpectedly discovered that ADAR proteins bind dsRNA substrates tandemly in vivo, each with a 50-bp footprint. | 32203492 |
2020-06-06 13:58:00 | AKT-1, -2, and -3 interact with both ADAR1p110 and ADAR2 and phosphorylate these RNA editases. Using site-directed mutagenesis of suspected AKT phosphorylation sites, AKT was found to primarily phosphorylate ADAR1p110 and ADAR2 on T738 and T553, respectively, and overexpression of the phosphomimic mutants ADAR1p110 (T738D) and ADAR2 (T553D) resulted in a 50-100% reduction in editase activity. | 31095429 |
Type | IDs |
---|---|
Synonymous | ADAR2, DRABA2, DRADA2, RED1 |
Gene |
UniProtKB-ID:
RED1_HUMAN
UniprotKB:
P78563
UniParc:
UPI0000133622,
UPI000002B233,
UPI000056F12E,
UPI0005A5D027,
UPI00005B2F02,
UPI000002B232
EMBL:
U82120,
AB194371,
U82121,
X99383,
BX322560,
AL163301,
U76421,
AB194372,
AL133499,
AF001042,
X99227,
U76422,
FJ169506,
U76420,
CH471079,
AB194370,
BC065545,
AB194373,
AF533142,
AP001579,
AY135659,
AF525422
Ensembl:
ENSG00000197381
KO:
hsa:104
|
Nucleutide sequences |
EMBL-CDS:
BAE16326.1,
AAB58300.1,
BAE16327.1,
AAC51240.1,
AAC51241.1,
AAM83100.1,
BAE16328.1,
EAX09360.1,
EAX09359.1,
AAB61687.1,
AAC51242.1,
CAA67762.1,
AAM97654.1,
EAX09357.1,
CAA67611.1,
ACN49027.1,
AAN10291.1,
CAB90493.1,
AAB61686.1,
AAH65545.1,
BAE16329.1
Ensembl_TRS:
ENST00000360697,
ENST00000496664,
ENST00000437626,
ENST00000492414,
ENST00000629643,
ENST00000348831,
ENST00000389863
|
Protein sequencees |
Ensembl_PRO:
ENSP00000436367,
ENSP00000374513,
ENSP00000435381,
ENSP00000353920,
ENSP00000486475,
ENSP00000015877,
ENSP00000414600
RefSeq:
XP_016883739.1,
XP_016883744.1,
XP_016883733.1,
XP_016883736.1,
NP_001103.1,
XP_016883742.1,
XP_016883734.1,
NP_001333616.1,
XP_016883743.1,
XP_011527727.1,
XP_016883738.1,
XP_016883740.1,
XP_016883732.1,
XP_006724017.1,
XP_016883735.1,
NP_056648.1,
XP_016883731.1,
NP_001333617.1,
NP_056649.1,
XP_024307811.1,
NP_001153702.1,
XP_016883737.1,
XP_011527734.1
|
Others |
UniRef100:
UniRef100_P78563
UniRef90:
UniRef90_P78563
UniRef50:
UniRef50_P78563
UniGene:
Hs.474018
CCDS:
CCDS33590.1,
CCDS42970.1,
CCDS33589.1
|
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Refseq |
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