| Type | Description |
|---|---|
| Definition | black spleen |
| Date | Results | Publications |
|---|---|---|
| 2017-12-23 12:24:00 | Studies made so far highlight the role of BSP in skeletal mineralization, as well as its importance for proper osteoblast and osteoclast differentiation and activity, most prominently in primary/repair bone. [review] | 26763578 |
| 2017-05-27 10:16:00 | Transfection assay demonstrated that Osx was able to activate Bsp promoter reporter in a dose-dependent manner. To define minimal region of Bsp promoter activated by Osx, a series of deletion mutants of Bsp promoter were generated, and the minimal region was narrowed down to the proximal 100 bp. Point-mutagenesis studies showed that one GC-rich site was required for Bsp promoter activation by Osx. | 27261434 |
| 2010-05-03 11:15:00 | BSP, but not OPN, plays a role in primary bone formation and mineralization of newly formed bone during the process of cortical bone healing. | 19761880 |
| 2010-01-21 00:00:00 | BSP deficiency impairs bone growth and mineralization, concomitant with reduced bone formation, but does not prevent the bone loss resulting from loss of mechanical stimulation. | 18458111 |
| Type | IDs |
|---|